{"id":"W2194728256","doi":"10.1016/j.bmcl.2015.11.066","title":"Synthesis and evaluation of 18F-labeled 4-nitrobenzyl derivatives for imaging tumor hypoxia with positron emission tomography: Comparison of 2-[18F]fluoroethyl carbonate and 2-[18F]fluoroethyl carbamate","year":2015,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Positron emission tomography; Carbonate; Hypoxia (environmental); Nuclear medicine; Radiochemistry; Organic chemistry; Oxygen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006556164,0.0005118077,0.0005677795,0.0003644591,0.000269122,0.0002991499,0.0007738833,0.0007743606,0.001061],"category_scores_gemma":[0.0006037612,0.0003657858,0.0002933524,0.0003584553,0.0002850281,0.0004186703,0.0002177773,0.000429753,0.0004651619],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004684341,"about_ca_system_score_gemma":0.0005314841,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002489729,"about_ca_topic_score_gemma":0.002704948,"domain_scores_codex":[0.9997396,0.00008441739,0.00001985948,0.00004167283,0.00005026631,0.00006407234],"domain_scores_gemma":[0.9996669,0.00005843636,0.00006943957,0.00004315518,0.00008408257,0.0000778819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008639449,0.000172686,0.0002351878,0.0001473513,0.00002863508,0.0003152447,0.00009959732,0.0008297059,0.9885375,0.0004385127,0.0001178287,0.008213736],"study_design_scores_gemma":[0.00009803322,0.001225427,0.0005461538,0.000006946894,0.00004864849,0.0003904285,0.00001613254,0.0008025154,0.9936274,0.00002350182,0.003200736,0.00001396204],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9610412,0.005572626,0.02722677,0.0002199073,0.00007161343,0.0006487645,0.0007486726,0.0001462078,0.004324262],"genre_scores_gemma":[0.9629459,0.003516286,0.02821217,0.00008656133,0.00003359119,0.0002180834,0.001425305,0.00009970894,0.003462331],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002489729,"threshold_uncertainty_score":0.004950523,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01822438500298547,"score_gpt":0.2728660765668905,"score_spread":0.254641691563905,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}