{"id":"W2195333861","doi":"10.1016/j.ymeth.2015.12.004","title":"Vascular smooth muscle cell differentiation from human stem/progenitor cells","year":2015,"lang":"en","type":"review","venue":"Methods","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"Heart and Stroke Foundation; University of Toronto; Toronto General Hospital; University Health Network; Ted Rogers Centre for Heart Research; Canada Research Chairs","funders":"Canadian Institutes of Health Research; Core Research for Evolutional Science and Technology; Heart and Stroke Foundation of Canada","keywords":"Induced pluripotent stem cell; Embryonic stem cell; Cell biology; Progenitor cell; Regenerative medicine; Stem cell; Vascular smooth muscle; Biology; Transplantation; Directed differentiation; Endothelial stem cell; Adult stem cell; Angiogenesis; Neural crest; Cancer research; Immunology; Anatomy; Medicine; Internal medicine; Endocrinology; Genetics; Smooth muscle; Embryo","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008906972,0.0008684141,0.0009470319,0.001627276,0.0002099595,0.0007748562,0.0008319652,0.0006786777,0.002153573],"category_scores_gemma":[0.0006728313,0.0003718683,0.0003657038,0.001193082,0.0005437951,0.0008861231,0.000629257,0.001543648,0.001970487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005782711,"about_ca_system_score_gemma":0.0009331377,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008192461,"about_ca_topic_score_gemma":0.001500921,"domain_scores_codex":[0.9998111,0.00002258206,0.00002942903,0.00003553991,0.00008288969,0.00001846729],"domain_scores_gemma":[0.9997906,0.0001008395,0.00002718317,0.000009675668,0.00005084878,0.00002085701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004792697,0.00004856152,0.0001764266,0.009898581,0.00004366602,0.0001335245,0.00002690629,0.0002161364,0.008212904,0.003407419,0.01624839,0.9615395],"study_design_scores_gemma":[0.0000193973,0.00006247597,0.0009124764,0.001848228,0.0001124597,0.0009157679,0.00003939164,0.000116776,0.006455893,0.002475833,0.9870135,0.00002782799],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002319615,0.9965246,0.001048762,0.0003026512,0.0003231468,0.00001054376,0.00004296294,0.00001899612,0.001496217],"genre_scores_gemma":[0.001043507,0.9959829,0.0009846219,0.0002065246,0.0001367481,0.00001694981,0.00009482033,0.000004146455,0.001529873],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002153573,"threshold_uncertainty_score":0.007204413,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09991577243707156,"score_gpt":0.4389027590341629,"score_spread":0.3389869865970914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}