{"id":"W2195341603","doi":"10.1016/j.clim.2015.12.004","title":"B cell development in chromosome 22q11.2 deletion syndrome","year":2015,"lang":"en","type":"article","venue":"Clinical Immunology","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"Izaak Walton Killam Health Centre; Dalhousie University","funders":"National Cancer Institute; National Institutes of Health; Baxalta","keywords":"Somatic hypermutation; Biology; Hypogammaglobulinemia; Population; Immunology; B cell; Genetics; Common variable immunodeficiency; Memory B cell; Antibody; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001429581,0.000284751,0.0006687258,0.0002236055,0.0001427482,0.00001402373,0.0005927552,0.0007944303,0.0004045294],"category_scores_gemma":[0.0004219502,0.0002719219,0.0001496427,0.0003282298,0.0006688116,0.0001437711,0.0002735961,0.0009972596,0.006900031],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001208629,"about_ca_system_score_gemma":0.0004086301,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009277762,"about_ca_topic_score_gemma":0.000009425206,"domain_scores_codex":[0.9966742,0.0006598403,0.001297372,0.0005566995,0.00005588609,0.0007559522],"domain_scores_gemma":[0.9988089,0.0002803371,0.0002465045,0.0005351341,0.0001087676,0.00002039341],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.005336095,0.02529636,0.1407091,0.0001937365,0.002513605,0.001301708,0.01465446,0.0004052969,0.359991,0.009092589,0.01393825,0.4265678],"study_design_scores_gemma":[0.01741114,0.001985029,0.2569017,0.0001306999,0.00007268031,0.0006664307,0.00242404,0.00001874735,0.02473989,0.00133036,0.6930088,0.001310496],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9524633,0.04012723,0.0001373712,0.0002682644,0.003086353,0.0002699592,0.000003202172,0.0001324638,0.003511883],"genre_scores_gemma":[0.996195,0.0002048547,0.0001109501,0.0003344335,0.000005608144,0.00005338138,0.0001564973,0.0000269667,0.002912262],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6790705,"threshold_uncertainty_score":0.9999733,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04402740421580826,"score_gpt":0.2991503834998625,"score_spread":0.2551229792840543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}