{"id":"W2195738902","doi":"10.1111/cei.12752","title":"Functional advantage of educated KIR2DL1+ natural killer cells for anti-HIV-1 antibody-dependent activation","year":2015,"lang":"en","type":"article","venue":"Clinical & Experimental Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Health and Medical Research Council; Medical Research Council; Canadian Institutes of Health Research","keywords":"Biology; Antibody-dependent cell-mediated cytotoxicity; Immunology; Antibody; Human leukocyte antigen; Interleukin 12; Major histocompatibility complex; Natural killer cell; Cell biology; Antigen; Cytotoxic T cell; Monoclonal antibody; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000440907,0.0002890213,0.0006063083,0.0001731824,0.0001538429,0.00001474185,0.0002514007,0.0005107905,0.001675043],"category_scores_gemma":[0.0003666111,0.0002654601,0.0003361322,0.0001255249,0.0005217694,0.0003108098,0.0001554828,0.0005767705,0.001128883],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001346869,"about_ca_system_score_gemma":0.0001549927,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000456239,"about_ca_topic_score_gemma":7.462322e-7,"domain_scores_codex":[0.9975761,0.0003614993,0.001056146,0.0005202739,0.00007266696,0.0004133138],"domain_scores_gemma":[0.9982269,0.0005301306,0.0004820197,0.0003853622,0.0003298548,0.00004571252],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002967796,0.001608592,0.00114792,0.00000647516,0.0004048377,9.210909e-7,0.000268439,0.000007077863,0.9469637,0.0005001824,0.04551065,0.0006133883],"study_design_scores_gemma":[0.006207594,0.001481654,0.006475406,0.00003531341,0.00004491885,0.00004703279,0.004321174,0.00001661336,0.9100221,0.00003383868,0.07103168,0.000282635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.93797,0.003059569,0.001161148,0.0002820388,0.05570662,0.000615082,0.00001132746,0.0001086722,0.001085511],"genre_scores_gemma":[0.9790581,0.00007473586,0.0001496727,0.000412578,0.0001661438,0.0000645893,0.001571161,0.00003559896,0.01846743],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05554048,"threshold_uncertainty_score":0.9999797,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04849948316723705,"score_gpt":0.3707444173683638,"score_spread":0.3222449342011268,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}