{"id":"W2196563970","doi":"10.1371/journal.pone.0138951","title":"Generation and Characterization of Live Attenuated Influenza A(H7N9) Candidate Vaccine Virus Based on Russian Donor of Attenuation","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Biomedical Advanced Research and Development Authority; Centers for Disease Control and Prevention; Chinese Center for Disease Control and Prevention; Public Health Agency; Public Health Agency of Canada","keywords":"Virology; Biology; Attenuated vaccine; Virus; Live attenuated influenza vaccine; Reassortment; Reverse genetics; Antigenicity; Influenza A virus; Hemagglutination assay; Viral replication; Gene; Microbiology; Influenza vaccine; Genetics; Genome; Antibody; Virulence; Medicine; Infectious disease (medical specialty)","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001323934,0.0003035664,0.0001887091,0.0002188151,0.0001354604,0.0001860948,0.0002346711,0.0002256996,0.0004756278],"category_scores_gemma":[0.0001379507,0.00008947544,0.0003099378,0.0001371847,0.0001253547,0.0001417078,0.0001312936,0.0002992712,0.0004031553],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001831801,"about_ca_system_score_gemma":0.0001430389,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008868698,"about_ca_topic_score_gemma":0.0006105935,"domain_scores_codex":[0.9999093,0.00001451989,0.000009414939,0.00002010715,0.00002943865,0.00001720581],"domain_scores_gemma":[0.9999225,0.00001213793,0.0000186098,0.00001136803,0.0000234071,0.00001202026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003893482,0.00002622337,0.0006305026,0.00001669957,0.000003073634,0.00003047309,0.00001292836,0.00009161728,0.9983745,0.00005805212,0.00001827207,0.0006986919],"study_design_scores_gemma":[0.00002552796,0.001137596,0.009299024,0.000007853448,0.00004138711,0.0004950808,0.00005409538,0.002050663,0.9826849,0.00005972854,0.004136608,0.000007574406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951206,0.0002575901,0.003245447,0.00002520256,0.00001274284,0.00009437474,0.0004368751,0.00001787637,0.0007893509],"genre_scores_gemma":[0.9831007,0.0003688102,0.009864288,0.00003639849,0.0000101214,0.00009643081,0.004356001,0.00002007767,0.002147273],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008868698,"threshold_uncertainty_score":0.001763403,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1735330004075238,"score_gpt":0.3358774344182991,"score_spread":0.1623444340107753,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}