{"id":"W2197124269","doi":"10.1038/cdd.2015.104","title":"MALT1 is an intrinsic regulator of regulatory T cells","year":2015,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"Fonds National de la Recherche Luxembourg; Canadian Institutes of Health Research; Alexander von Humboldt-Stiftung","keywords":"Regulator; Autoimmunity; Biology; Cell biology; Immune system; Inflammation; TLR2; Effector; Immunology; Cancer research; Innate immune system; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001066872,0.0004919099,0.0002410659,0.0002273215,0.0001611798,0.0004228127,0.0002460524,0.0002592663,0.001530317],"category_scores_gemma":[0.0001589754,0.0001221747,0.0001972779,0.0001409406,0.0002030503,0.0002622368,0.000334899,0.0004833561,0.0005872829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002592732,"about_ca_system_score_gemma":0.0001237869,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002130096,"about_ca_topic_score_gemma":0.0002089709,"domain_scores_codex":[0.9998423,0.00002106937,0.000009401702,0.00005008151,0.00003987069,0.00003718896],"domain_scores_gemma":[0.999853,0.00001346801,0.0000674105,0.00001090301,0.00001912797,0.0000361105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001213675,0.00000791517,0.0009749293,0.00006410649,0.000005100456,0.0001480826,0.00001516605,0.00004389408,0.9959489,0.0001009087,0.00005494573,0.002514738],"study_design_scores_gemma":[0.00003763257,0.0005805104,0.04674436,0.00004376117,0.00008000347,0.00422875,0.0001034485,0.001577569,0.9259561,0.0003391525,0.02028667,0.00002202012],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.97074,0.01928259,0.006649372,0.0002663664,0.00007761276,0.00002500102,0.0005645402,0.0002378448,0.002156552],"genre_scores_gemma":[0.9929091,0.003492702,0.001013946,0.00006989492,0.0000532673,0.00001645557,0.0005249453,0.00002782021,0.00189191],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001530317,"threshold_uncertainty_score":0.005119443,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01784690558921505,"score_gpt":0.2129965915273492,"score_spread":0.1951496859381341,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}