{"id":"W2198641492","doi":"10.1038/srep10423","title":"Unique somatic and malignant expression patterns implicate PIWI-interacting RNAs in cancer-type specific biology","year":2015,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Chromosomal and Genetic Variations","field":"Agricultural and Biological Sciences","cited_by":167,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Occupational Cancer Research Centre; BC Cancer Agency","funders":"Canadian Institutes of Health Research; Terry Fox Foundation; Canada's Michael Smith Genome Sciences Centre","keywords":"Piwi-interacting RNA; Germline; Biology; Somatic cell; Transcriptome; Gene silencing; Cancer; Genetics; Gene; Computational biology; Gene expression; RNA; RNA interference","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001133729,0.0001392223,0.0001554477,0.0004358189,0.0001824891,0.0002915599,0.00009516467,0.000151469,0.001240569],"category_scores_gemma":[0.0002942221,0.000137589,0.0001798028,0.0003177511,0.0002247256,0.0001738973,0.0002720864,0.0002216532,0.0003370542],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009012625,"about_ca_system_score_gemma":0.0001086973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001724165,"about_ca_topic_score_gemma":0.0003223667,"domain_scores_codex":[0.9998991,0.000009920547,0.00000897243,0.00004273773,0.00002211363,0.00001712022],"domain_scores_gemma":[0.9998258,0.00005572005,0.00004865127,0.00002537106,0.00001862147,0.00002590037],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001666316,0.00001261463,0.038295,0.00006782801,0.0000261609,0.0003347231,0.0001409499,0.00009077854,0.9536183,0.0002250256,0.00004589705,0.006976011],"study_design_scores_gemma":[0.00001345148,0.0002660976,0.7241995,0.00001278463,0.0001080364,0.005018945,0.0002268442,0.001608194,0.2637952,0.001133289,0.003597581,0.00002007649],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954141,0.0005251166,0.002454134,0.00002222675,0.000003829759,0.000009872414,0.0003870775,0.00004477475,0.001138759],"genre_scores_gemma":[0.9970861,0.0002604506,0.001362358,0.00001619546,0.000004823991,0.000009542061,0.000621423,0.0000139853,0.0006250906],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001240569,"threshold_uncertainty_score":0.004150152,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05515615830237126,"score_gpt":0.2857035098173983,"score_spread":0.2305473515150271,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}