{"id":"W2198641492","doi":"10.1038/srep10423","title":"Unique somatic and malignant expression patterns implicate PIWI-interacting RNAs in cancer-type specific biology","year":2015,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Chromosomal and Genetic Variations","field":"Agricultural and Biological Sciences","cited_by":167,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Occupational Cancer Research Centre; BC Cancer Agency","funders":"Canadian Institutes of Health Research; Terry Fox Foundation; Canada's Michael Smith Genome Sciences Centre","keywords":"Piwi-interacting RNA; Germline; Biology; Somatic cell; Transcriptome; Gene silencing; Cancer; Genetics; Gene; Computational biology; Gene expression; RNA; RNA interference","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005590517,0.0001058671,0.0001456815,0.00002790466,0.0001669072,0.0001470703,0.0001052025,0.00006208777,0.0001991708],"category_scores_gemma":[0.00007419802,0.00004333783,0.00002896572,0.0003367332,0.0000619064,0.0001004766,0.0001248223,0.0000779718,0.00001007124],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003774977,"about_ca_system_score_gemma":0.00002944081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006362064,"about_ca_topic_score_gemma":0.001227976,"domain_scores_codex":[0.9986649,0.00007227595,0.0003475546,0.0005275132,0.0001375014,0.0002502132],"domain_scores_gemma":[0.9993902,0.00006242548,0.0001881164,0.0001287877,0.00009249695,0.0001379907],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000004360769,0.0000439659,0.157705,0.000004252394,0.000001903694,0.00003885425,0.0002951644,0.00001087761,0.8292263,0.0000310033,0.0004771488,0.01216124],"study_design_scores_gemma":[0.0003477244,0.0003190171,0.4807642,0.0004645739,0.0000161922,0.0006221298,0.00171401,0.0004948799,0.2972688,0.04417984,0.1730874,0.0007213068],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996399,0.0003495836,0.00001077316,0.0006201155,0.002161086,0.0001907337,0.000007486318,0.00003091587,0.000230326],"genre_scores_gemma":[0.9993333,0.000034096,0.0001204267,0.00002586233,0.0001110642,0.00002102916,0.00006180976,0.000001006919,0.0002914143],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5319574,"threshold_uncertainty_score":0.218078,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05515615830237126,"score_gpt":0.2857035098173983,"score_spread":0.2305473515150271,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}