{"id":"W2198879547","doi":"10.1182/blood.v122.21.2340.2340","title":"Regulation Of Factor VIII Clearance By Mannose-Binding Lectins","year":2013,"lang":"en","type":"article","venue":"Blood","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Glycan; Mannose; Mannan-binding lectin; Recombinant DNA; Lectin; Mannose receptor; Asialoglycoprotein receptor; Chemistry; Internalization; Mannan; Biochemistry; Von Willebrand factor; Glycosylation; Molecular biology; Receptor; Biology; Glycoprotein; In vitro; Immunology; Polysaccharide; Platelet; Hepatocyte","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001591817,0.0001644137,0.0001551567,0.0001803108,0.0001303198,0.0003622699,0.0001543197,0.0002575986,0.000646138],"category_scores_gemma":[0.0002150039,0.00007346254,0.000213142,0.00009303949,0.0001694206,0.000149258,0.0001424173,0.0002813567,0.0002546279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007719951,"about_ca_system_score_gemma":0.0001993102,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001161864,"about_ca_topic_score_gemma":0.0005167474,"domain_scores_codex":[0.9998109,0.00005029752,0.000009382321,0.00002773643,0.0000414522,0.00006019951],"domain_scores_gemma":[0.9998863,0.00002043322,0.00002538973,0.000007600333,0.00003380466,0.00002647934],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001388114,0.00001756812,0.0002826688,0.00002017398,0.000003724715,0.00002937428,0.000007686432,0.00004481021,0.9979522,0.0001150257,0.00005924619,0.001328785],"study_design_scores_gemma":[0.00002857388,0.0002682503,0.01706648,0.000009879135,0.00001512072,0.0002514788,0.00004032662,0.004739598,0.9729868,0.0001770178,0.004407018,0.00000960523],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932566,0.002885168,0.001951707,0.0001127305,0.00001847749,0.00002223942,0.0001436397,0.00005604705,0.001553444],"genre_scores_gemma":[0.9961581,0.0004750824,0.001351008,0.00006923742,0.000009546007,0.00001817082,0.000186022,0.000009067746,0.001723924],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001161864,"threshold_uncertainty_score":0.005601287,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02437393619616724,"score_gpt":0.2885417514664949,"score_spread":0.2641678152703277,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}