{"id":"W2201364792","doi":"10.1083/jcb.201503135","title":"In vivo single-particle imaging of nuclear mRNA export in budding yeast demonstrates an essential role for Mex67p","year":2015,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; University of Alberta","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"Nuclear pore; Messenger RNP; Cell biology; Cytoplasm; Ribonucleoprotein; Nuclear export signal; Nuclear transport; Saccharomyces cerevisiae; RNA; Biology; Messenger RNA; RNA-binding protein; Yeast; Biophysics; Chemistry; Cell nucleus; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009510094,0.00006835121,0.0001538669,0.00006053285,0.00002138559,0.000008123254,0.0002216029,0.00005515802,0.000008963265],"category_scores_gemma":[0.00009760742,0.00004924976,0.00004680249,0.00006399176,0.00009830396,0.00001328404,0.00005069602,0.00009749737,5.994148e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000166022,"about_ca_system_score_gemma":0.00008697273,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006270412,"about_ca_topic_score_gemma":0.00006017899,"domain_scores_codex":[0.9991724,0.000142474,0.0003103804,0.00008505781,0.00006589433,0.000223718],"domain_scores_gemma":[0.9995054,0.00002579931,0.0001650008,0.0001119502,0.0001127568,0.0000791004],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005210705,0.00009543214,0.005104359,0.000005056807,0.000008514551,0.000004635698,0.0001915543,0.0001705171,0.9933743,0.000035532,0.0000746492,0.0004143781],"study_design_scores_gemma":[0.0009531977,0.000694652,0.0002364238,0.00001113957,0.000007352635,0.00004267126,0.001395932,0.001810596,0.9938126,0.0003223206,0.0006562129,0.00005687307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987571,0.0004948251,0.0001877572,0.0001444127,0.00006245469,0.00007115509,0.000003277938,9.977192e-7,0.0002780786],"genre_scores_gemma":[0.9992705,0.0000539244,0.0004491938,0.0000519525,0.0001259393,9.471788e-7,0.000001710392,0.000009634757,0.00003617665],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004867936,"threshold_uncertainty_score":0.2008347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01643283468000418,"score_gpt":0.2810689995915629,"score_spread":0.2646361649115587,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}