{"id":"W2202120994","doi":"10.3899/jrheum.150599","title":"Rapid and Sustained Response to Tocilizumab in Patients with Polymyalgia Rheumatica Resistant or Intolerant to Glucocorticoids: A Multicenter Open-label Study","year":2016,"lang":"en","type":"letter","venue":"The Journal of Rheumatology","topic":"Vasculitis and related conditions","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Université de Franche-Comté; Institut National de la Santé et de la Recherche Médicale","keywords":"Medicine; Polymyalgia rheumatica; Tocilizumab; Giant cell arteritis; Internal medicine; Methotrexate; Gastroenterology; Interleukin 6; Vasculitis; Surgery; Disease; Cytokine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00364213,0.001047156,0.004275798,0.0003353703,0.0005421077,0.001252572,0.0008291692,0.002492308,0.003917551],"category_scores_gemma":[0.003465687,0.0004671949,0.002540117,0.0006268502,0.0007722585,0.00118251,0.0003202821,0.002509336,0.0005817154],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004889787,"about_ca_system_score_gemma":0.0006152956,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002606555,"about_ca_topic_score_gemma":0.0003926805,"domain_scores_codex":[0.9989391,0.0005070975,0.0001497607,0.0001581824,0.0001499275,0.00009590197],"domain_scores_gemma":[0.9955233,0.001501931,0.001460644,0.0002246158,0.0003739966,0.0009154826],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.840163,0.02354829,0.02781015,0.008431492,0.008098115,0.001345338,0.0003646269,0.0004229143,0.01103771,0.000189002,0.005041328,0.07354803],"study_design_scores_gemma":[0.6071671,0.3042075,0.07192972,0.0005199894,0.005557867,0.001096977,0.000194076,0.001484552,0.001071854,0.0001742811,0.006453436,0.0001426691],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9603987,0.03238663,0.0004997675,0.001908163,0.001400767,0.001505591,0.0008718269,0.0000587259,0.0009698062],"genre_scores_gemma":[0.9769,0.009193418,0.001249876,0.004547083,0.003980985,0.001917275,0.0009423086,0.00002645569,0.001242633],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004275798,"threshold_uncertainty_score":0.01926166,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01528782893981277,"score_gpt":0.2767339781745471,"score_spread":0.2614461492347343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}