{"id":"W2202120994","doi":"10.3899/jrheum.150599","title":"Rapid and Sustained Response to Tocilizumab in Patients with Polymyalgia Rheumatica Resistant or Intolerant to Glucocorticoids: A Multicenter Open-label Study","year":2016,"lang":"en","type":"letter","venue":"The Journal of Rheumatology","topic":"Vasculitis and related conditions","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Université de Franche-Comté; Institut National de la Santé et de la Recherche Médicale","keywords":"Medicine; Polymyalgia rheumatica; Tocilizumab; Giant cell arteritis; Internal medicine; Methotrexate; Gastroenterology; Interleukin 6; Vasculitis; Surgery; Disease; Cytokine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001331208,0.0004059395,0.001509362,0.0007526436,0.0001533069,0.00006252069,0.000604754,0.0003596945,0.0002200672],"category_scores_gemma":[0.0009564467,0.0001825462,0.00006661568,0.0003570739,0.0001577136,0.0001113015,0.0003166344,0.001373627,0.00002940727],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003021452,"about_ca_system_score_gemma":0.0006231494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002705364,"about_ca_topic_score_gemma":0.0001847886,"domain_scores_codex":[0.9957913,0.001254431,0.001433634,0.0003323358,0.0005871325,0.0006012113],"domain_scores_gemma":[0.9967865,0.001026922,0.0006611866,0.0006693327,0.0005780151,0.0002780683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.4929484,0.004451507,0.05532727,0.0007488937,0.004818378,0.005749626,0.02610767,0.00000262853,0.0002063587,0.00003343223,0.4010733,0.008532459],"study_design_scores_gemma":[0.4120585,0.1336404,0.2817043,0.03567879,0.004312632,0.01786514,0.01549568,0.00003685059,0.00002913178,0.0002217362,0.09665743,0.00229944],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6820596,0.0001768643,0.00004353322,0.3150916,0.0001592246,0.002415554,0.00002325426,0.000008249334,0.00002219213],"genre_scores_gemma":[0.9434353,0.0003155751,0.0006147193,0.05424032,0.00004142671,0.0001038602,0.00001123095,0.0001064416,0.00113114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3044159,"threshold_uncertainty_score":0.7444019,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01528782893981277,"score_gpt":0.2767339781745471,"score_spread":0.2614461492347343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}