{"id":"W2202356078","doi":"10.1016/j.carres.2015.10.008","title":"Mechanism-based candidate inhibitors of uridine diphosphate galactopyranose mutase (UGM)","year":2015,"lang":"en","type":"article","venue":"Carbohydrate Research","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan; Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Mutase; Chemistry; Uridine; Stereochemistry; Enzyme; Sulfonium; Uridine diphosphate; Biochemistry; Transition (genetics); Gene; RNA; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003425388,0.0008666451,0.0005085756,0.0004482821,0.0002783771,0.0007687507,0.0008760173,0.0006119871,0.003883801],"category_scores_gemma":[0.0001924173,0.0002491684,0.0004575217,0.0002416241,0.0002248282,0.0004341224,0.0003600434,0.0009701392,0.0008616602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000751941,"about_ca_system_score_gemma":0.0003998785,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004994948,"about_ca_topic_score_gemma":0.00137799,"domain_scores_codex":[0.9998802,0.0000184785,0.000005668397,0.00002321798,0.00002869842,0.00004369356],"domain_scores_gemma":[0.999941,0.00001046286,0.00001843727,0.000004253553,0.00001027913,0.00001553723],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001884486,0.001322668,0.001458219,0.001159111,0.0001866963,0.001000086,0.00009224103,0.00457539,0.8399124,0.01630094,0.006724413,0.1253834],"study_design_scores_gemma":[0.001003553,0.006730705,0.002148879,0.000126536,0.0002371171,0.001821366,0.00005914567,0.008019125,0.8987618,0.001684705,0.07934657,0.00006040632],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7392295,0.1262812,0.06183479,0.002775417,0.001443165,0.001845069,0.003169456,0.001977864,0.06144363],"genre_scores_gemma":[0.939357,0.03056482,0.01261572,0.0005800047,0.0001027479,0.0003328614,0.001309542,0.00004528985,0.01509205],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003883801,"threshold_uncertainty_score":0.01299262,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07068701533918231,"score_gpt":0.3237685995334703,"score_spread":0.2530815841942879,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}