{"id":"W2202470170","doi":"10.1182/blood.v124.21.5670.5670","title":"A Phase II Study of AT7519M, a CDK Inhibitor, in Patients with Chronic Lymphocytic Leukemia: NCIC CTG Trial IND.193","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; Juravinski Cancer Centre; Kingston General Hospital; Princess Margaret Cancer Centre; CancerCare Manitoba; University of Toronto","funders":"","keywords":"Medicine; Tumor lysis syndrome; Internal medicine; Chronic lymphocytic leukemia; Regimen; Gastroenterology; Cytopenia; Febrile neutropenia; Oncology; Neutropenia; Leukemia; Immunology; Chemotherapy; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001421915,0.001503698,0.001406047,0.0005814761,0.0004533979,0.000800254,0.001294774,0.001245283,0.004567767],"category_scores_gemma":[0.000664541,0.0003867991,0.0008837794,0.0007918922,0.001002947,0.0005336252,0.0003395602,0.003007209,0.000939792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001139065,"about_ca_system_score_gemma":0.002260904,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003917063,"about_ca_topic_score_gemma":0.006763508,"domain_scores_codex":[0.9996561,0.0001695156,0.00001428639,0.00004884047,0.00003285427,0.00007836839],"domain_scores_gemma":[0.9994532,0.00008788688,0.00005782228,0.00004006195,0.00003359864,0.0003274409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7346827,0.0594378,0.01132711,0.001409472,0.001177521,0.0007253622,0.0003642536,0.004559347,0.05154142,0.0007468527,0.01291334,0.1211148],"study_design_scores_gemma":[0.7233732,0.2584353,0.01017508,0.00004978802,0.0003004888,0.0003028464,0.00003658427,0.001071312,0.00240041,0.0001594971,0.003662714,0.00003276707],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848449,0.003360315,0.0005208214,0.000760878,0.0001232843,0.00407007,0.002126594,0.0001674097,0.004025711],"genre_scores_gemma":[0.9833142,0.002093548,0.00203184,0.00124113,0.0001838532,0.004175762,0.003664155,0.00003090342,0.003264711],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004567767,"threshold_uncertainty_score":0.01528072,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0125148004423638,"score_gpt":0.2805970150934022,"score_spread":0.2680822146510384,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}