{"id":"W2202874374","doi":"10.1530/erc-15-0045","title":"Autotaxin is an inflammatory mediator and therapeutic target in thyroid cancer","year":2015,"lang":"en","type":"article","venue":"Endocrine Related Cancer","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; University of Alberta","keywords":"Autotaxin; Mediator; Thyroid cancer; Thyroid; Medicine; Inflammation; Cancer research; Cancer; Internal medicine; Neuroscience; Oncology; Biology; Lysophosphatidic acid; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001741651,0.0001778912,0.0001912177,0.00006727136,0.00003541974,0.00001885769,0.0001309272,0.0001144473,0.0001449476],"category_scores_gemma":[0.00002974328,0.0001616706,0.0000369064,0.0001223216,0.00005803099,0.00001082781,0.00006331789,0.0001809622,0.000005408684],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003662118,"about_ca_system_score_gemma":0.0002469302,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005114952,"about_ca_topic_score_gemma":0.000229569,"domain_scores_codex":[0.998871,0.00007268832,0.000236455,0.0003571578,0.0001492422,0.0003134821],"domain_scores_gemma":[0.9994333,0.000006086697,0.00007466351,0.0002321326,0.00006451875,0.0001892783],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003146386,0.0001009109,0.1589805,0.00005394511,0.0002637077,0.000046963,0.002636157,0.002665204,0.8165423,0.0003269509,0.004460992,0.01360775],"study_design_scores_gemma":[0.007212708,0.0002843753,0.01959767,0.00008963134,0.0001055138,0.00005071973,0.0005698725,0.002831119,0.529859,0.0009266319,0.4375134,0.000959347],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9274738,0.07123768,0.00001186345,0.0003726119,0.0004405931,0.0001371425,0.00002208642,0.0000236358,0.0002806308],"genre_scores_gemma":[0.9930748,0.004823216,0.0001029133,0.0006341261,0.0004805494,0.00009798002,0.00002685587,0.00003863115,0.0007209496],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4330524,"threshold_uncertainty_score":0.6592734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01588283169369096,"score_gpt":0.2840353588239547,"score_spread":0.2681525271302637,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}