{"id":"W2204209053","doi":"10.1136/gutjnl-2015-310814","title":"Interaction between tumour-infiltrating B cells and T cells controls the progression of hepatocellular carcinoma","year":2015,"lang":"en","type":"article","venue":"Gut","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":469,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Biomedical Research Council; National Medical Research Council; Medical Research Council; Servier; Agency for Science, Technology and Research; Genentech; Partenariat Canadien Contre Le Cancer","keywords":"Flow cytometry; CD40; Hepatocellular carcinoma; CD38; Immunophenotyping; Granzyme B; Cancer research; Immunohistochemistry; Immunofluorescence; Biology; CD19; Granzyme; Pathology; CD3; Immune system; CD34; T cell; Medicine; Immunology; CD8; Cytotoxic T cell; Perforin; Stem cell; In vitro; Antibody","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001893924,0.0001984353,0.0002115801,0.0002393644,0.0001239343,0.0003303993,0.00009254142,0.0001305577,0.00145003],"category_scores_gemma":[0.0002788555,0.00009140513,0.00009045395,0.0001944644,0.000184167,0.0001580558,0.0001611051,0.0001837392,0.0005374789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002187679,"about_ca_system_score_gemma":0.0001449348,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008382697,"about_ca_topic_score_gemma":0.0004763204,"domain_scores_codex":[0.9998816,0.0000328756,0.000007938593,0.00002431492,0.00002212242,0.0000310055],"domain_scores_gemma":[0.9997819,0.00002546227,0.0000984167,0.00001120234,0.00002325847,0.00005978179],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003136651,0.0001669977,0.1461911,0.0003035507,0.00006929632,0.0008392945,0.0002811825,0.0005841414,0.8220642,0.0001602145,0.0002949711,0.02590844],"study_design_scores_gemma":[0.00008954856,0.00167296,0.9134403,0.00004808555,0.00009593626,0.002169529,0.0005130641,0.00217927,0.07559933,0.0001351719,0.004043999,0.0000128623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971448,0.001943402,0.0002771222,0.00002324801,0.000003979239,0.000008242054,0.00004450181,0.00001790631,0.0005367994],"genre_scores_gemma":[0.9989181,0.0004666936,0.0001063087,0.000008060293,0.000006829379,0.000008895483,0.00004940486,0.000003135233,0.0004326057],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00145003,"threshold_uncertainty_score":0.004850864,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03675056090626577,"score_gpt":0.2951979399451888,"score_spread":0.258447379038923,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}