{"id":"W2204603896","doi":"10.1186/s13287-015-0262-3","title":"“Mouse Clone Model” for evaluating the immunogenicity and tumorigenicity of pluripotent stem cells","year":2015,"lang":"en","type":"article","venue":"Stem Cell Research & Therapy","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Discovery Centre; University of Toronto","funders":"","keywords":"Induced pluripotent stem cell; Stem cell; Biology; clone (Java method); Immunogenicity; Somatic cell; Cloning (programming); Embryonic stem cell; Cell biology; Immune system; Immunology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009237803,0.0008203439,0.0004137785,0.001340869,0.000300366,0.0003685868,0.0004797639,0.0006803543,0.002683089],"category_scores_gemma":[0.0004413862,0.0001959856,0.0005342631,0.000346509,0.0003579727,0.0006176932,0.0003938088,0.001154942,0.0005451267],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002853729,"about_ca_system_score_gemma":0.0003984977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005648233,"about_ca_topic_score_gemma":0.0006311664,"domain_scores_codex":[0.9995053,0.0001382561,0.00007346213,0.0001011578,0.0001059779,0.00007582067],"domain_scores_gemma":[0.9993736,0.0001744263,0.000107099,0.0001262147,0.00009682269,0.0001218445],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003488557,0.0003074838,0.0009072805,0.00009061792,0.00001834717,0.0001468239,0.00004648761,0.00016242,0.9936113,0.001381142,0.0002288441,0.00275049],"study_design_scores_gemma":[0.00005473794,0.002665421,0.001649852,0.00001623007,0.00007560293,0.0006183795,0.00003361566,0.001221987,0.9890357,0.0002713685,0.004343188,0.00001399055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8749045,0.00281766,0.1101238,0.0003795717,0.0003610953,0.001161662,0.002813627,0.0007610981,0.006677022],"genre_scores_gemma":[0.9321687,0.002714557,0.0525759,0.0002519432,0.00007055043,0.001612263,0.00386739,0.0001508886,0.006587963],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002683089,"threshold_uncertainty_score":0.008975863,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1666523031831005,"score_gpt":0.3886238425476189,"score_spread":0.2219715393645184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}