{"id":"W2205706443","doi":"10.1016/j.bmcl.2015.10.043","title":"Incorporation of cyclic azobenzene into oligodeoxynucleotides for the photo-regulation of DNA hybridization","year":2015,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Photochromic and Fluorescence Chemistry","field":"Materials Science","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"Brock University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Phosphoramidite; Chemistry; Oligonucleotide; Azobenzene; Förster resonance energy transfer; DNA; Fluorescence; Fluorescein; Combinatorial chemistry; Stereochemistry; Photochemistry; Biochemistry; Organic chemistry; Molecule","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005537951,0.0001572571,0.0002509065,0.00002119285,0.00006997194,0.00001366001,0.0003537195,0.00008498431,0.000144977],"category_scores_gemma":[0.0003851031,0.0001208944,0.00006189126,0.0001768598,0.0003386097,0.0001191489,0.00005109138,0.00007200849,0.000004093456],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001213788,"about_ca_system_score_gemma":0.0001621706,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001050253,"about_ca_topic_score_gemma":0.000002178745,"domain_scores_codex":[0.9986547,0.00001986985,0.000483003,0.0002523162,0.000413247,0.0001768923],"domain_scores_gemma":[0.9987655,0.0001109384,0.000477157,0.0003504905,0.0002014679,0.00009449906],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009481938,0.000033158,0.0002431992,0.0002196351,0.00001265421,5.597769e-7,0.0003691795,0.00004464786,0.9969113,0.00001064654,0.00189764,0.0001625406],"study_design_scores_gemma":[0.000637424,0.00002402595,0.0007620162,0.00009108154,0.00006446207,0.00001144342,0.0003684105,0.0006688159,0.9969468,0.000207402,0.0001015256,0.0001165905],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903008,0.0001342803,0.008066774,0.0009331075,0.0001663678,0.0002702857,0.00001967754,0.0000320008,0.00007665227],"genre_scores_gemma":[0.998495,0.000008612928,0.0008876726,0.0001815338,0.0003010293,0.00002502495,0.00006481441,0.00001833907,0.00001799858],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00819412,"threshold_uncertainty_score":0.492993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01919784763039613,"score_gpt":0.2376027890705401,"score_spread":0.2184049414401439,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}