{"id":"W2206043086","doi":"10.1371/journal.pone.0143158","title":"Black Tea Extract and Its Theaflavin Derivatives Inhibit the Growth of Periodontopathogens and Modulate Interleukin-8 and β-Defensin Secretion in Oral Epithelial Cells","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Oral microbiology and periodontitis research","field":"Dentistry","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Theaflavin; Secretion; Chemistry; Defensin; Black tea; Beta defensin; Polyphenol; Antimicrobial; Microbiology; Pharmacology; Biochemistry; Biology; Food science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007224952,0.0003861497,0.0002968473,0.0002778246,0.0001494434,0.0001736671,0.0001031494,0.0002289086,0.00117079],"category_scores_gemma":[0.0001035363,0.00008788449,0.0003640144,0.0001512028,0.0001185831,0.0001686119,0.0001701697,0.0002801325,0.0001655378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000831194,"about_ca_system_score_gemma":0.0001585334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000479691,"about_ca_topic_score_gemma":0.0006469039,"domain_scores_codex":[0.9999384,0.0000141305,0.00000598036,0.0000100308,0.00001166991,0.00001984313],"domain_scores_gemma":[0.9999373,0.00001388735,0.00001945679,0.000005890839,0.000006374097,0.00001721105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002866369,0.00008541885,0.00012275,0.00007042181,0.00001003189,0.00003134404,0.00001645541,0.00003470158,0.9964483,0.00001312199,0.00002100073,0.002859854],"study_design_scores_gemma":[0.00005971957,0.002365852,0.01132553,0.00001927066,0.00005410842,0.0002252094,0.00006189697,0.0003590359,0.9824812,0.00005850615,0.002982471,0.000007220602],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943145,0.004185421,0.0005954077,0.0001152431,0.00002086431,0.00001642388,0.0001294663,0.00003041417,0.0005923237],"genre_scores_gemma":[0.9935805,0.003033007,0.001138501,0.0001047376,0.00001965077,0.00002499027,0.0002284604,0.00001186927,0.001858308],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00117079,"threshold_uncertainty_score":0.003916681,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05618612440310229,"score_gpt":0.2714976764311436,"score_spread":0.2153115520280413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}