{"id":"W2206264177","doi":"10.1002/bies.201500157","title":"HMGNs: The enhancer charmers","year":2015,"lang":"en","type":"review","venue":"BioEssays","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Canadian Institutes of Health Research","keywords":"Chromatin; Enhancer; Nucleosome; Histone; Biology; ChIA-PET; Genetics; Enhancer RNAs; Promoter; Transcription (linguistics); Cell biology; Transcription factor; Gene; Computational biology; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004515415,0.0007903004,0.0008303049,0.001719334,0.0003658475,0.001161424,0.001002702,0.001228754,0.00617988],"category_scores_gemma":[0.0004453924,0.000316512,0.0003743364,0.001052666,0.0006336385,0.001248644,0.0008132206,0.001707611,0.007141436],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007644329,"about_ca_system_score_gemma":0.001004616,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007874697,"about_ca_topic_score_gemma":0.0008694006,"domain_scores_codex":[0.9998569,0.00001784915,0.0000173235,0.00003546952,0.00005270568,0.00001979072],"domain_scores_gemma":[0.9998502,0.00003888594,0.00002962467,0.000008557518,0.00004150245,0.00003120802],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001320896,0.00004522851,0.0002599318,0.007482802,0.00006542781,0.0002675884,0.00009093928,0.0003860466,0.008975557,0.01310435,0.03568696,0.9335031],"study_design_scores_gemma":[0.00000607325,0.00002534388,0.0001825181,0.0004013672,0.00002082285,0.0004470757,0.00001730138,0.00002480098,0.001586462,0.0009604767,0.9963192,0.000008539275],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003831499,0.9934043,0.0006303856,0.0004318671,0.0005333391,0.00001595337,0.0001091545,0.00006753218,0.004424223],"genre_scores_gemma":[0.004773253,0.9835231,0.001240506,0.0008857567,0.0004002761,0.00003682861,0.0004290948,0.00001934794,0.008691889],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00617988,"threshold_uncertainty_score":0.02067369,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03983239046185976,"score_gpt":0.324620997489217,"score_spread":0.2847886070273572,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}