{"id":"W2206585231","doi":"10.1016/j.mito.2015.07.099","title":"Rotenone-elevated mitochondrial respiration with inflammatory myopathies indicates a secondary impairment to NADH: Ubiquinone oxidoreductase that attenuates succinate dehydrogenase activity","year":2015,"lang":"en","type":"article","venue":"Mitochondrion","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"Pathophysiology; Mitochondrial disease; Disease; Mitochondrial DNA; Internal medicine; Medicine; Cyclic vomiting syndrome; Biology; Bioinformatics; Migraine; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003345228,0.0006851625,0.0003441082,0.0005861815,0.0003025346,0.0002493228,0.0002850539,0.0005571491,0.003410144],"category_scores_gemma":[0.0002925664,0.0003067714,0.0003293169,0.00031395,0.0005352614,0.0004893781,0.0003270251,0.0007436646,0.0004060912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001980837,"about_ca_system_score_gemma":0.0001246141,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002898172,"about_ca_topic_score_gemma":0.0005434593,"domain_scores_codex":[0.9997659,0.00003996785,0.00003738275,0.00005703049,0.00004933403,0.00005030164],"domain_scores_gemma":[0.9997668,0.00002301852,0.0001032151,0.0000328518,0.00002183913,0.00005233276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001463807,0.00009050278,0.002030638,0.00008942783,0.00002547094,0.001377095,0.00004053661,0.00003452116,0.9930294,0.0001224071,0.00006390864,0.001632407],"study_design_scores_gemma":[0.0002611242,0.002748359,0.1475182,0.00003575221,0.0001165953,0.01397715,0.000186715,0.0009565019,0.832338,0.0003750473,0.001471094,0.00001535617],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929669,0.00145444,0.003195395,0.0001456723,0.00006433087,0.0000556441,0.000245696,0.0001136649,0.001758421],"genre_scores_gemma":[0.9977183,0.0002823388,0.0008809489,0.00004364581,0.00001478406,0.0000299064,0.0001934003,0.000009591288,0.0008270467],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003410144,"threshold_uncertainty_score":0.01140803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01819427169868524,"score_gpt":0.2419510447840111,"score_spread":0.2237567730853259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}