{"id":"W2208164594","doi":"10.1093/mutage/gev070","title":"Genotoxicity of flubendazole and its metabolites<i>in vitro</i>and the impact of a new formulation on<i>in vivo</i>aneugenicity","year":2015,"lang":"en","type":"article","venue":"Mutagenesis","topic":"Parasitic Diseases Research and Treatment","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Health Canada; Drugs for Neglected Diseases initiative; Bill and Melinda Gates Foundation","keywords":"Ames test; Micronucleus test; Genotoxicity; Pharmacology; In vivo; Metabolite; Micronucleus; Biology; Chemistry; Toxicity; Biochemistry; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002374018,0.0003936977,0.0002231877,0.0002263193,0.00009062317,0.0001890255,0.0001552313,0.0003119947,0.0008650681],"category_scores_gemma":[0.0003531774,0.0001158832,0.0002443852,0.0001317542,0.0002001048,0.0001651871,0.0001081953,0.0003051452,0.0001484312],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002507838,"about_ca_system_score_gemma":0.0001642132,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001023566,"about_ca_topic_score_gemma":0.001443571,"domain_scores_codex":[0.9997141,0.0001260998,0.00002325363,0.00004597015,0.00006579685,0.00002481588],"domain_scores_gemma":[0.9998047,0.00004948787,0.00006856722,0.00001741181,0.00004415525,0.00001575597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003482568,0.00004800166,0.0003748714,0.0000609103,0.00001262845,0.00005415315,0.00001290098,0.0001404777,0.9961773,0.00001487621,0.00002449918,0.002731047],"study_design_scores_gemma":[0.00002604055,0.005577614,0.004376766,0.000009903854,0.00004073313,0.0002529179,0.00002490218,0.0003458013,0.9880541,0.000009740681,0.001275344,0.000006070854],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928622,0.004182081,0.001675845,0.0000740276,0.0000227358,0.00005368705,0.000211991,0.00001729622,0.0009001828],"genre_scores_gemma":[0.9936845,0.002189059,0.002513409,0.00005195083,0.00001151851,0.00003210579,0.0003301653,0.00001178197,0.001175591],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001023566,"threshold_uncertainty_score":0.002893925,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0399134318887255,"score_gpt":0.3455502532159158,"score_spread":0.3056368213271903,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}