{"id":"W2208235309","doi":"10.1073/pnas.1515898113","title":"Dissecting the interface between apicomplexan parasite and host cell: Insights from a divergent AMA–RON2 pair","year":2015,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Toxoplasma gondii Research Studies","field":"Immunology and Microbiology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; Alliance Française contre les Maladies Parasitaires; Agence Nationale de la Recherche; Canadian Light Source; Government of Canada; Canadian Institute for Advanced Research","keywords":"Biology; Plasmodium falciparum; Rhoptry; Toxoplasma gondii; Intracellular parasite; Plasmodium (life cycle); Host adaptation; Parasite hosting; Cell biology; Genetics; Apicomplexa; Gene; Genome; Antibody; Malaria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000739495,0.00009674196,0.0001654597,0.00008023317,0.0004259817,0.00002241377,0.0007195679,0.00007733931,0.000008950063],"category_scores_gemma":[0.0007698375,0.00004945045,0.00003982912,0.0002927963,0.001653999,0.000215685,0.0005939925,0.0002711217,0.000006666085],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002835212,"about_ca_system_score_gemma":0.00002498784,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006067022,"about_ca_topic_score_gemma":9.27454e-7,"domain_scores_codex":[0.9990776,0.00002449767,0.0002245762,0.0002225859,0.0002816065,0.0001691145],"domain_scores_gemma":[0.9990194,0.0004455521,0.0002616787,0.00001036556,0.0002396886,0.00002328709],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000321656,0.00003874451,0.3205839,0.00002382807,0.0001061535,6.235855e-9,0.004470819,0.000008309189,0.6670962,0.004940019,0.002562718,0.000137143],"study_design_scores_gemma":[0.0002512426,0.00006924073,0.4663792,0.00004189449,0.00001616455,0.00000171221,0.002629938,0.00001696177,0.516717,0.01241606,0.001395336,0.00006533151],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993383,0.001871487,7.848483e-7,0.002874694,0.00004336571,0.0001634846,0.00003400823,0.00001142167,0.001617728],"genre_scores_gemma":[0.9993855,0.00002832579,0.00009675585,0.00004758194,0.00004653974,0.000007742328,3.589258e-7,0.000002777351,0.0003843726],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1503792,"threshold_uncertainty_score":0.6094226,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08116915046000236,"score_gpt":0.3406691371970842,"score_spread":0.2594999867370819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}