{"id":"W2208235309","doi":"10.1073/pnas.1515898113","title":"Dissecting the interface between apicomplexan parasite and host cell: Insights from a divergent AMA–RON2 pair","year":2015,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Toxoplasma gondii Research Studies","field":"Immunology and Microbiology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; Alliance Française contre les Maladies Parasitaires; Agence Nationale de la Recherche; Canadian Light Source; Government of Canada; Canadian Institute for Advanced Research","keywords":"Biology; Plasmodium falciparum; Rhoptry; Toxoplasma gondii; Intracellular parasite; Plasmodium (life cycle); Host adaptation; Parasite hosting; Cell biology; Genetics; Apicomplexa; Gene; Genome; Antibody; Malaria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001012136,0.0002115535,0.000226999,0.0001803283,0.0002558505,0.0003692486,0.000314286,0.0002960624,0.0004902939],"category_scores_gemma":[0.00007649231,0.0001249776,0.0001791432,0.00008570046,0.0002483439,0.000742769,0.0003879063,0.0003802654,0.0002204203],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002102971,"about_ca_system_score_gemma":0.0001183728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000244257,"about_ca_topic_score_gemma":0.0003652147,"domain_scores_codex":[0.9999603,0.000007696435,0.000002434483,0.00001089511,0.00001064371,0.000008096113],"domain_scores_gemma":[0.9999732,0.000003465324,0.000006817867,0.000002843254,0.000003615235,0.00001016477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007010853,0.000008725974,0.001290578,0.00004491659,0.000007944688,0.0003627225,0.00006632281,0.0002179811,0.9948319,0.0008208842,0.00005126315,0.002226586],"study_design_scores_gemma":[0.00005125926,0.000541962,0.07862696,0.00005395949,0.0001187827,0.007782796,0.001658395,0.05425759,0.8197413,0.005361433,0.03172741,0.00007809293],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902479,0.002663998,0.005462225,0.0002479976,0.00001276553,0.000004928743,0.00005337657,0.00004901698,0.001257735],"genre_scores_gemma":[0.9929451,0.001085529,0.005065009,0.00008019165,0.00001371533,0.00000622751,0.00013861,0.00001493107,0.000650683],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004902939,"threshold_uncertainty_score":0.00164026,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08116915046000236,"score_gpt":0.3406691371970842,"score_spread":0.2594999867370819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}