{"id":"W2209001804","doi":"10.1152/ajpcell.00347.2014","title":"Role of nitric oxide in murine conventional outflow physiology","year":2015,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Glaucoma and retinal disorders","field":"Medicine","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Eye Institute; Allergan Foundation; Home Office; Whitaker International Fellows and Scholars Program; Imperial College London; Fight for Sight UK; Allergan; Research to Prevent Blindness","keywords":"Enos; Outflow; Nitric oxide; Trabecular meshwork; Chemistry; Nitric oxide synthase; Intraocular pressure; Nitric Oxide Synthase Type III; Internal medicine; Snap; Endocrinology; Glaucoma; Green fluorescent protein; Schlemm's canal; Andrology; Medicine; Biochemistry; Ophthalmology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003373167,0.0003284994,0.001649198,0.0005299308,0.00003161118,0.000002258816,0.0003650119,0.0001568891,0.0001506598],"category_scores_gemma":[0.0001689997,0.0002573532,0.0004551179,0.0006198196,0.001286317,0.00009099096,0.000120013,0.0006810403,0.00005471111],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008613228,"about_ca_system_score_gemma":0.0004345371,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002231736,"about_ca_topic_score_gemma":0.000005160347,"domain_scores_codex":[0.9972832,0.0004719511,0.001040887,0.0003801823,0.0002748577,0.000548883],"domain_scores_gemma":[0.9973351,0.0002354834,0.001229709,0.0003584178,0.0005379795,0.0003032734],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.003531893,0.001216171,0.007730873,0.00007562667,0.000161898,0.00001479799,0.0001665993,0.0002866955,0.9851218,0.0001251866,0.0008492411,0.0007192551],"study_design_scores_gemma":[0.006180445,0.00563851,0.9489641,0.00009676525,0.0001523891,0.0002337374,0.003041776,0.0002435277,0.02536491,0.007774849,0.002011318,0.0002976289],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977264,0.0007963866,0.00001307581,0.0003724164,0.0001957745,0.0001945627,0.00000825004,0.00001456134,0.0006785292],"genre_scores_gemma":[0.9977134,0.0001885406,0.001094259,0.000544713,0.0002759224,0.000008860159,0.00003646256,0.00003479205,0.0001030189],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9597569,"threshold_uncertainty_score":0.9999878,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008094717831956482,"score_gpt":0.2464472218823384,"score_spread":0.2383525040503819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}