{"id":"W2209447716","doi":"10.1159/000381475","title":"Independent Proteolytic Activities Control the Stability and Size of <b><i>Drosophila </i></b>Inhibitor of Apoptosis 2 Protein","year":2015,"lang":"en","type":"article","venue":"Journal of Innate Immunity","topic":"Invertebrate Immune Response Mechanisms","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canada Research Chairs; Alberta Innovates - Health Solutions","keywords":"Inhibitor of apoptosis; Biology; Innate immune system; Apoptosis; Cell biology; Signal transduction; Ubiquitin; XIAP; Caspase; Inhibitor of apoptosis domain; Immune system; Ubiquitin ligase; Programmed cell death; Immunology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001446164,0.0004354404,0.0001678858,0.0003122015,0.0001659025,0.0004780099,0.0002555687,0.0002485467,0.0006776781],"category_scores_gemma":[0.0002077212,0.0001876573,0.0002278653,0.0001420448,0.0003081368,0.0003479536,0.0002042351,0.0004666652,0.0004315439],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006747655,"about_ca_system_score_gemma":0.0002228129,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000521392,"about_ca_topic_score_gemma":0.00110602,"domain_scores_codex":[0.9998544,0.00001463244,0.0000148206,0.00005315673,0.00003360357,0.00002939793],"domain_scores_gemma":[0.9997081,0.00003648724,0.0001395073,0.00002402514,0.00003719539,0.00005457559],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004133685,0.000005774423,0.0003488847,0.0000140549,0.000002807257,0.00002795613,0.000007560267,0.00002617858,0.9985883,0.0001269766,0.00002603957,0.0007841118],"study_design_scores_gemma":[0.00001191065,0.00008634548,0.01269997,0.000004838245,0.00001252215,0.0004763094,0.00003100372,0.001385589,0.9830027,0.0001024879,0.002180186,0.000006037594],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990503,0.002180997,0.005294059,0.00007892143,0.00002030838,0.00001921121,0.0004077035,0.00007106672,0.001424799],"genre_scores_gemma":[0.993066,0.0007540065,0.003699542,0.00004130632,0.000008310492,0.00002000808,0.0006205356,0.00003142572,0.001758941],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006776781,"threshold_uncertainty_score":0.004895806,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01598993868486541,"score_gpt":0.2268734275916072,"score_spread":0.2108834889067418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}