{"id":"W2209448786","doi":"10.1016/s1470-2045(15)00462-3","title":"Pretreatment with anti-thymocyte globulin versus no anti-thymocyte globulin in patients with haematological malignancies undergoing haemopoietic cell transplantation from unrelated donors: a randomised, controlled, open-label, phase 3, multicentre trial","year":2015,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":363,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; University of British Columbia; Princess Margaret Cancer Centre; Vancouver General Hospital; BC Children's Hospital; Université Laval; Hôpital de l'Enfant-Jésus; Child and Family Research Institute; BC Cancer Agency; Hôtel-Dieu de Québec; CancerCare Manitoba; Capital District Health Authority; University of Toronto; Dalhousie University; Royal Victoria Hospital; Centre hospitalier universitaire de Québec; McMaster University; Hôpital Maisonneuve-Rosemont; Juravinski Hospital","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Anti-thymocyte globulin; Medicine; Transplantation; Internal medicine; Graft-versus-host disease; Clinical endpoint; Gastroenterology; Globulin; Immunosuppression; Randomized controlled trial; Surgery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001074968,0.0005809088,0.002497029,0.0001279313,0.000149788,0.00008831688,0.0004500577,0.0004007032,0.00009150417],"category_scores_gemma":[0.0002576289,0.0003370913,0.00009533353,0.0004070189,0.0002917534,0.0002373206,0.00005194154,0.0004921595,0.0001373904],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005653058,"about_ca_system_score_gemma":0.0008861045,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004656599,"about_ca_topic_score_gemma":0.0008132021,"domain_scores_codex":[0.9954256,0.001268402,0.001072904,0.0007700587,0.0006678869,0.0007950782],"domain_scores_gemma":[0.9957536,0.002437722,0.0005920053,0.0005911046,0.0003164112,0.0003091016],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9715972,0.005144163,0.01644598,0.0002299806,0.0006776799,0.001598172,0.002955857,0.0005178541,0.0003283033,0.00004269533,0.000153006,0.0003091213],"study_design_scores_gemma":[0.9727405,0.01485426,0.005171027,0.0007526784,0.002234206,0.00007784805,0.0006739175,0.001428748,0.001413309,0.00002469157,0.000204425,0.0004243673],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837565,0.0005669974,0.0008634069,0.0009872826,0.0005689919,0.01015413,0.0001303711,0.0001242743,0.002848053],"genre_scores_gemma":[0.9916679,0.00097033,0.005395924,0.0003457452,0.0001877758,0.0005285263,0.0007640513,0.00006106865,0.00007868914],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01127495,"threshold_uncertainty_score":0.9999081,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06285534341132204,"score_gpt":0.3304848937193195,"score_spread":0.2676295503079975,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}