{"id":"W2209448786","doi":"10.1016/s1470-2045(15)00462-3","title":"Pretreatment with anti-thymocyte globulin versus no anti-thymocyte globulin in patients with haematological malignancies undergoing haemopoietic cell transplantation from unrelated donors: a randomised, controlled, open-label, phase 3, multicentre trial","year":2015,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":363,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; University of British Columbia; Princess Margaret Cancer Centre; Vancouver General Hospital; BC Children's Hospital; Université Laval; Hôpital de l'Enfant-Jésus; Child and Family Research Institute; BC Cancer Agency; Hôtel-Dieu de Québec; CancerCare Manitoba; Capital District Health Authority; University of Toronto; Dalhousie University; Royal Victoria Hospital; Centre hospitalier universitaire de Québec; McMaster University; Hôpital Maisonneuve-Rosemont; Juravinski Hospital","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Anti-thymocyte globulin; Medicine; Transplantation; Internal medicine; Graft-versus-host disease; Clinical endpoint; Gastroenterology; Globulin; Immunosuppression; Randomized controlled trial; Surgery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001369763,0.002189676,0.004375491,0.0003729462,0.0004585257,0.001257839,0.001054831,0.002303845,0.006502775],"category_scores_gemma":[0.001542255,0.0006572188,0.002496243,0.0005371435,0.001979838,0.001485661,0.0004362866,0.004101263,0.001175833],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008006739,"about_ca_system_score_gemma":0.0009449205,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008381858,"about_ca_topic_score_gemma":0.0017178,"domain_scores_codex":[0.9993831,0.0003508176,0.00002808038,0.0001112042,0.00002481408,0.0001019634],"domain_scores_gemma":[0.9991515,0.0003271558,0.0001380472,0.00007182862,0.00003274752,0.0002787918],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9891441,0.002643243,0.0001920509,0.0003096228,0.000376741,0.00002190059,0.00003449577,0.0001880219,0.001320435,0.00005393907,0.0002589681,0.005456485],"study_design_scores_gemma":[0.9358319,0.06261359,0.0006005756,0.00002271487,0.0002218303,0.00001711284,0.00002002956,0.0001785977,0.0001610389,0.0001184979,0.0002024145,0.00001179869],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901239,0.004523174,0.0006175733,0.0007058922,0.0008141689,0.001520319,0.0004773011,0.0001014854,0.001116152],"genre_scores_gemma":[0.991026,0.002453123,0.001050735,0.0009330344,0.0005057337,0.001538386,0.0005474621,0.00002310346,0.001922344],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006502775,"threshold_uncertainty_score":0.02175397,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06285534341132204,"score_gpt":0.3304848937193195,"score_spread":0.2676295503079975,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}