{"id":"W2210794007","doi":"10.1016/j.scr.2015.12.007","title":"Cyclosporin A enhances neurogenesis in the dentate gyrus of the hippocampus","year":2015,"lang":"en","type":"article","venue":"Stem Cell Research","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Neurogenesis; Dentate gyrus; Subventricular zone; Biology; Neural stem cell; Hippocampus; In vivo; Precursor cell; Neuroscience; In vitro; Cell biology; Stem cell; Pharmacology; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001078763,0.000220793,0.0002534805,0.0003017443,0.0001243354,0.0002280938,0.0001098765,0.0001379583,0.001098231],"category_scores_gemma":[0.0001326161,0.00008148684,0.000158243,0.0001838256,0.0002153256,0.000201854,0.0001410257,0.000520274,0.000211198],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001680658,"about_ca_system_score_gemma":0.0003091381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005411887,"about_ca_topic_score_gemma":0.001141035,"domain_scores_codex":[0.9999434,0.00001110354,0.000008212239,0.000009112044,0.00001674209,0.0000115215],"domain_scores_gemma":[0.9998195,0.00003196669,0.00004123924,0.00001479647,0.00001570388,0.00007677806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002594259,0.00006940754,0.0002230774,0.00006299879,0.000006883848,0.00004218795,0.00001612385,0.00005856596,0.995052,0.00009093619,0.00005393169,0.004064457],"study_design_scores_gemma":[0.00004668202,0.001258625,0.01159942,0.00001612188,0.00004605652,0.0001651449,0.0000481415,0.0004102351,0.9833651,0.00009036868,0.00294952,0.000004490764],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952521,0.001650927,0.0006853426,0.00008770913,0.00004087919,0.00001267925,0.0001475571,0.00007724973,0.002045486],"genre_scores_gemma":[0.991418,0.003613475,0.001642241,0.00004510957,0.00004961968,0.00001920965,0.000255867,0.00002190512,0.002934545],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001098231,"threshold_uncertainty_score":0.003673971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1866582965812054,"score_gpt":0.3586609319329213,"score_spread":0.1720026353517159,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}