{"id":"W2210809984","doi":"10.1016/s0168-8278(15)31044-8","title":"P0842 : Malachite-I: Phase 3B Trial of ombitasvir/paritaprevir/r and dasabuvir +/− ribavirin or telaprevir + peginterferon/ribavirin in treatment-naïve adults with HCV genotype 1","year":2015,"lang":"en","type":"article","venue":"Journal of Hepatology","topic":"Hepatitis C virus research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Island Health","funders":"","keywords":"Ombitasvir; Dasabuvir; Ribavirin; Paritaprevir; Telaprevir; Medicine; Gastroenterology; Internal medicine; Ledipasvir; Virology; Pharmacology; Chronic hepatitis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00126684,0.002203765,0.002229035,0.0003982558,0.0004935217,0.001390902,0.001276616,0.001511024,0.01274599],"category_scores_gemma":[0.001011555,0.0008544038,0.001845075,0.0004008248,0.001155537,0.00112632,0.0006394178,0.004968283,0.003255962],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008950508,"about_ca_system_score_gemma":0.001532796,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001473023,"about_ca_topic_score_gemma":0.004027391,"domain_scores_codex":[0.9996204,0.0001771419,0.00001285719,0.00005806777,0.00003102473,0.0001004307],"domain_scores_gemma":[0.999627,0.00004773441,0.00005557832,0.00002851246,0.00001882037,0.0002223949],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8539616,0.01560811,0.002229296,0.001047501,0.001776799,0.0001493525,0.0002264302,0.001672754,0.01276005,0.0006601275,0.01262632,0.09728178],"study_design_scores_gemma":[0.9021818,0.0884898,0.003766143,0.00004983513,0.0003561671,0.0001629616,0.00004836206,0.00060522,0.0008966325,0.000331131,0.003080451,0.00003154368],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9743612,0.004621178,0.0009233549,0.003006413,0.0006475654,0.003618718,0.004482601,0.0008513994,0.007487529],"genre_scores_gemma":[0.9669574,0.003595546,0.003301536,0.003766857,0.0003752029,0.004240817,0.006365955,0.0001689439,0.01122773],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01274599,"threshold_uncertainty_score":0.04263961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08609405534584083,"score_gpt":0.3924095117714936,"score_spread":0.3063154564256527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}