{"id":"W2213525681","doi":"10.1038/ncb3232","title":"Fumarate in DNA repair","year":2015,"lang":"en","type":"letter","venue":"Nature Cell Biology","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"National Cancer Institute","keywords":"Fumarase; Histone; DNA demethylation; DNA; Cell biology; DNA repair; DNA damage; Enzyme; Chemistry; Biochemistry; Biology; DNA methylation; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002745912,0.0008303805,0.000946373,0.0004041903,0.001854869,0.002536714,0.00114823,0.02047067,0.003119725],"category_scores_gemma":[0.008779487,0.0004702122,0.0006785784,0.0002292128,0.003124669,0.002694892,0.001905477,0.02025016,0.002152415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002331364,"about_ca_system_score_gemma":0.001299277,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001225499,"about_ca_topic_score_gemma":0.002027896,"domain_scores_codex":[0.9988542,0.0003962531,0.0001208461,0.0001509455,0.0003274791,0.0001503619],"domain_scores_gemma":[0.9974684,0.00161425,0.0001609837,0.0001467827,0.0002694428,0.0003401905],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004399579,0.00007611747,0.0005739168,0.0001770953,0.0000475261,0.002404161,0.00009837078,0.0002144045,0.001486144,0.02833623,0.9266444,0.03950164],"study_design_scores_gemma":[0.0003562984,0.0001657463,0.000772888,0.0002440192,0.00006569215,0.001641469,0.000188471,0.0008842312,0.003111748,0.06220025,0.9303125,0.00005675426],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.001028956,0.01713554,0.0005178159,0.9385186,0.03866876,0.00001285547,0.00004135426,0.00004051698,0.004035526],"genre_scores_gemma":[0.04174144,0.01987828,0.001074799,0.7889159,0.128861,0.00007221665,0.00004804165,0.0000326527,0.01937567],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.02047067,"threshold_uncertainty_score":0.01691526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007465657319612213,"score_gpt":0.2439688076675555,"score_spread":0.2365031503479433,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}