{"id":"W2213525681","doi":"10.1038/ncb3232","title":"Fumarate in DNA repair","year":2015,"lang":"en","type":"letter","venue":"Nature Cell Biology","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"National Cancer Institute","keywords":"Fumarase; Histone; DNA demethylation; DNA; Cell biology; DNA repair; DNA damage; Enzyme; Chemistry; Biochemistry; Biology; DNA methylation; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0004180605,0.000482302,0.0004950094,0.0001820955,0.00002689162,0.00001189589,0.0005899661,0.008921747,0.0000653375],"category_scores_gemma":[0.0001471515,0.0004406308,0.000270289,0.0001449849,0.0001110907,0.000001826629,0.0003173002,0.003148035,0.0001380293],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000710524,"about_ca_system_score_gemma":0.0002722009,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001710549,"about_ca_topic_score_gemma":0.00004603378,"domain_scores_codex":[0.9973682,0.0003471553,0.0003625954,0.001112384,0.0001497847,0.0006598931],"domain_scores_gemma":[0.9985558,0.00002741337,0.0001973873,0.0009917585,0.0001510557,0.00007661414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003868076,0.0000223825,0.00009173108,0.00004831342,0.00003641588,0.0001646043,0.000007187778,0.000001223784,0.1934099,0.00001566961,0.8060063,0.0001575581],"study_design_scores_gemma":[0.0004729819,0.0003446202,0.000009912818,0.00001382392,0.0000206902,0.00002425856,0.000005079139,0.000007243849,0.09775809,0.0004671896,0.9004324,0.0004436765],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.2996584,0.08444101,0.0001314494,0.3510924,0.02399824,0.004324322,0.001401766,0.0009809074,0.2339715],"genre_scores_gemma":[0.04953381,0.0005570228,0.001734352,0.8903214,0.009477297,0.0001355736,0.01181256,0.0002266064,0.03620143],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.5392289,"threshold_uncertainty_score":0.9998046,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007465657319612213,"score_gpt":0.2439688076675555,"score_spread":0.2365031503479433,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}