{"id":"W2213860215","doi":"10.1002/hbm.23091","title":"Early detection of Alzheimer's disease using M<scp>RI</scp> hippocampal texture","year":2015,"lang":"en","type":"article","venue":"Human Brain Mapping","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":212,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; University of California, San Diego; Eurostars; Genentech; National Institutes of Health; IXICO; H. Lundbeck A/S; National Institute on Aging; Commonwealth Scientific and Industrial Research Organisation; Nordea-fonden; Eisai; Højteknologifonden; Servier; Eli Lilly and Company; Lundbeckfonden; Pfizer; Biogen; BioClinica; Hjerteforeningen; Northern California Institute for Research and Education; Velux Stiftung; F. Hoffmann-La Roche; Synarc; University of Southern California; Medpace; Bristol-Myers Squibb; Meso Scale Diagnostics; Villum Fonden; Novartis Pharmaceuticals Corporation; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Hippocampal formation; Alzheimer's disease; Texture (cosmology); Neuroscience; Hippocampus; Disease; Psychology; Medicine; Artificial intelligence; Computer science; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004465758,0.0004690823,0.0003086928,0.001102471,0.0002512836,0.0007890185,0.0004233598,0.0003839028,0.001183972],"category_scores_gemma":[0.002446634,0.0001407369,0.0003986637,0.0007225674,0.0003202748,0.000349173,0.0004591927,0.0003006992,0.0003743965],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002641049,"about_ca_system_score_gemma":0.0001624878,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0109059,"about_ca_topic_score_gemma":0.01872824,"domain_scores_codex":[0.9997845,0.00003769864,0.00002765983,0.00005853767,0.00006544806,0.00002621427],"domain_scores_gemma":[0.999054,0.0001034549,0.000495169,0.00009990042,0.0001227297,0.0001246577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004259362,0.00002640034,0.9935337,0.00001627405,0.00007960846,0.0001180447,0.00005068326,0.0001585178,0.001589366,0.00002270988,0.0001969686,0.003781724],"study_design_scores_gemma":[0.00000540585,0.00008008975,0.9985934,0.00000309267,0.00001784602,0.0002918911,0.00002870175,0.0005125985,0.0003235686,0.00002892303,0.0001107308,0.000003862864],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987538,0.0001047831,0.0002058675,0.00002097418,0.000004973592,0.00001326878,0.0004533338,0.00001862975,0.0004242853],"genre_scores_gemma":[0.9986506,0.00004622958,0.0004372467,0.00001137602,0.000007938776,0.00000645232,0.0005836,0.00000342872,0.0002531017],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0109059,"threshold_uncertainty_score":0.02168483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07450364463098154,"score_gpt":0.3338524924667862,"score_spread":0.2593488478358047,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}