{"id":"W2213860215","doi":"10.1002/hbm.23091","title":"Early detection of Alzheimer's disease using M<scp>RI</scp> hippocampal texture","year":2015,"lang":"en","type":"article","venue":"Human Brain Mapping","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":212,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; University of California, San Diego; Eurostars; Genentech; National Institutes of Health; IXICO; H. Lundbeck A/S; National Institute on Aging; Commonwealth Scientific and Industrial Research Organisation; Nordea-fonden; Eisai; Højteknologifonden; Servier; Eli Lilly and Company; Lundbeckfonden; Pfizer; Biogen; BioClinica; Hjerteforeningen; Northern California Institute for Research and Education; Velux Stiftung; F. Hoffmann-La Roche; Synarc; University of Southern California; Medpace; Bristol-Myers Squibb; Meso Scale Diagnostics; Villum Fonden; Novartis Pharmaceuticals Corporation; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Hippocampal formation; Alzheimer's disease; Texture (cosmology); Neuroscience; Hippocampus; Disease; Psychology; Medicine; Artificial intelligence; Computer science; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006228891,0.0001628142,0.0002488785,0.0003001623,0.0001656173,0.00004458766,0.00009262903,0.00007304487,0.00005255057],"category_scores_gemma":[0.0004750106,0.0001559218,0.0001246518,0.0003005292,0.0001274978,0.0001559449,0.00008720024,0.0002411363,0.00003955272],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000708295,"about_ca_system_score_gemma":0.0001529124,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000642645,"about_ca_topic_score_gemma":0.0000037939,"domain_scores_codex":[0.9983083,0.0001344918,0.0002839992,0.0002879117,0.0006000985,0.0003851879],"domain_scores_gemma":[0.9988259,0.00007702213,0.0001178989,0.0002483963,0.0002921707,0.0004385846],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001107171,0.00041616,0.2760133,0.0002846262,0.0004453108,0.0002164491,0.003089799,0.00001609631,0.704315,0.0002395283,0.002268132,0.01258487],"study_design_scores_gemma":[0.002296075,0.0004333321,0.9854302,0.0003222421,0.0002313653,0.00002105665,0.001859978,0.001156126,0.003536125,0.001407948,0.003208832,0.00009675857],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903114,0.0005589418,0.004544195,0.000137865,0.000089077,0.0005293176,0.000005025461,0.00006944336,0.003754664],"genre_scores_gemma":[0.9983674,0.000002064998,0.0001587897,0.0002921678,0.0003066166,0.00001852479,0.00002222132,0.00002933542,0.0008028814],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7094169,"threshold_uncertainty_score":0.6358308,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07450364463098154,"score_gpt":0.3338524924667862,"score_spread":0.2593488478358047,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}