{"id":"W2214017990","doi":"10.1177/135965350901400104","title":"Safety, pharmacokinetics and antiviral effect of BILB 1941, a novel hepatitis C virus RNA polymerase inhibitor, after 5 days oral treatment","year":2009,"lang":"en","type":"article","venue":"Antiviral Therapy","topic":"Hepatitis C virus research","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"Boehringer Ingelheim (Canada)","funders":"","keywords":"Gastroenterology; Medicine; Internal medicine; Hepatitis C virus; Adverse effect; Placebo; Population; Pharmacokinetics; Hepatitis C; Viral load; Pharmacology; Immunology; Virology; Virus; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003225074,0.000451342,0.0008471396,0.0002841996,0.00009185514,0.00004252956,0.0001167769,0.0001559542,0.00007873706],"category_scores_gemma":[0.00003608363,0.0003325879,0.0002320565,0.0004059513,0.0002662073,0.0002157692,0.00004480974,0.0002543002,0.00003259588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001028865,"about_ca_system_score_gemma":0.00009941933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001642238,"about_ca_topic_score_gemma":0.0001203104,"domain_scores_codex":[0.997633,0.0002360602,0.0004858623,0.000496736,0.0005562411,0.0005920473],"domain_scores_gemma":[0.9990479,0.000151091,0.0001132961,0.0004139566,0.00008360676,0.0001901584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003886824,0.0006116737,0.1474995,0.00002728109,0.0001551261,0.0002093318,0.0002162493,1.953627e-7,0.4314663,0.00001396256,0.0001421605,0.4157714],"study_design_scores_gemma":[0.01320661,0.01231742,0.1260363,0.0001397095,0.0001008125,0.00001871146,0.00000391223,0.0003940292,0.8411798,0.00001448437,0.006263429,0.0003247393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938965,0.002566569,0.00008867459,0.0005927001,0.0001376864,0.001140402,0.0002206172,0.0001375312,0.00121926],"genre_scores_gemma":[0.9766931,0.02173267,0.0003342557,0.0005424471,0.0002612469,0.00004117384,0.00003854025,0.00008525734,0.0002713171],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4154467,"threshold_uncertainty_score":0.9999126,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02176250953072437,"score_gpt":0.3329568586103003,"score_spread":0.3111943490795759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}