{"id":"W2214994713","doi":"","title":"A study on genetic mutations involving mitochondrial disorders diagnostic approach and application of human iPSCs to understand disease pathogenesis","year":2015,"lang":"en","type":"article","venue":"Työväentutkimus Vuosikirja","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Pathogenesis; Disease; Mitochondrial disease; Induced pluripotent stem cell; Genetics; Biology; Mutation; Medicine; Computational biology; Bioinformatics; Gene; Mitochondrial DNA; Pathology; Immunology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006032651,0.0002234019,0.0002004717,0.0005074147,0.0002519625,0.0004323657,0.0002107098,0.0004473995,0.001582797],"category_scores_gemma":[0.0003196601,0.00008744578,0.0003468257,0.0002459855,0.0002557949,0.0002406775,0.0003116044,0.000384141,0.0004096532],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001826884,"about_ca_system_score_gemma":0.0002333407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003115456,"about_ca_topic_score_gemma":0.0002244857,"domain_scores_codex":[0.9997266,0.00003272977,0.00003252366,0.00007936866,0.0001053647,0.00002336153],"domain_scores_gemma":[0.9998732,0.00003338415,0.0000163127,0.00002057601,0.00003829001,0.00001824238],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001548161,0.0001096641,0.003405214,0.0001998028,0.00002363536,0.0009132564,0.0002519547,0.0003658009,0.9603043,0.001272777,0.0004009283,0.03259795],"study_design_scores_gemma":[0.00005136636,0.001234499,0.02680951,0.00009932732,0.0002121177,0.005913135,0.0003981181,0.003479233,0.9128795,0.001045655,0.04784933,0.00002821422],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9460348,0.008757379,0.03183236,0.0006307105,0.0003383466,0.0002872382,0.001138287,0.0001559667,0.0108249],"genre_scores_gemma":[0.9527901,0.01121667,0.02437177,0.000555288,0.00014546,0.0003652615,0.001877963,0.00006662789,0.008610844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001582797,"threshold_uncertainty_score":0.005294979,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02711230747869789,"score_gpt":0.2794979376993578,"score_spread":0.2523856302206599,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}