{"id":"W2215721454","doi":"10.1186/s13293-015-0053-7","title":"Derivation of consensus inactivation status for X-linked genes from genome-wide studies","year":2015,"lang":"en","type":"article","venue":"Biology of Sex Differences","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":271,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"X-inactivation; Gene; Genetics; XIST; Biology; Dosage compensation; X chromosome; Epigenetics; Genome; Chromosome; Skewed X-inactivation; Gene silencing; Human genome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008676762,0.0006112404,0.0008390077,0.005322646,0.0007138209,0.00167657,0.0009547836,0.0005708171,0.001706022],"category_scores_gemma":[0.01831636,0.0001901455,0.001042749,0.003266935,0.0004415332,0.0006284838,0.001958954,0.0006952086,0.000542762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004757438,"about_ca_system_score_gemma":0.0009044153,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001197201,"about_ca_topic_score_gemma":0.002557634,"domain_scores_codex":[0.9943198,0.0009510879,0.001077287,0.001755966,0.00157509,0.0003207653],"domain_scores_gemma":[0.9816782,0.008418884,0.003238853,0.002097597,0.004079777,0.0004866515],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007117934,0.00006874434,0.8374948,0.002178381,0.00193237,0.0005292909,0.001430545,0.001668761,0.06605407,0.000991718,0.002120554,0.08481899],"study_design_scores_gemma":[0.0000449342,0.0002319882,0.9519978,0.0003626668,0.00225743,0.001381554,0.001247665,0.006003951,0.01939811,0.002162577,0.01484982,0.00006139915],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9261926,0.005312441,0.05058816,0.0002141214,0.0001041946,0.0003698645,0.01189995,0.0004675931,0.00485115],"genre_scores_gemma":[0.9427966,0.0009518747,0.04046463,0.0001203825,0.00003624281,0.0003480971,0.01452682,0.0001704641,0.0005850108],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008676762,"threshold_uncertainty_score":0.04588771,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07517913122856572,"score_gpt":0.3244062454854613,"score_spread":0.2492271142568955,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}