{"id":"W2216252985","doi":"10.1371/journal.pone.0144114","title":"Genome-Wide Gene by Environment Interaction Analysis Identifies Common SNPs at 17q21.2 that Are Associated with Increased Body Mass Index Only among Asthmatics","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Air Force Materiel Command; National Center for Research Resources; National Institute of Allergy and Infectious Diseases; Yale School of Public Health, Yale University; Canadian Institutes of Health Research; U.S. Air Force; Georgia Clinical and Translational Science Alliance; Yale University; National Institutes of Health; National Heart, Lung, and Blood Institute; U.S. Environmental Protection Agency","keywords":"Asthma; Framingham Heart Study; Medicine; Single-nucleotide polymorphism; Body mass index; Overweight; Obesity; Genome-wide association study; Odds ratio; SNP; Offspring; Allele; Internal medicine; Genetics; Framingham Risk Score; Gene; Biology; Genotype; Disease; Pregnancy","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006542472,0.000559669,0.0005727292,0.0007997978,0.0004264582,0.000598142,0.0003695377,0.0004795173,0.001825759],"category_scores_gemma":[0.001112146,0.0002915543,0.001394187,0.001048243,0.0003470314,0.0001345259,0.0004077776,0.0006145858,0.0001391371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001388519,"about_ca_system_score_gemma":0.0003365449,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003207536,"about_ca_topic_score_gemma":0.00636941,"domain_scores_codex":[0.9992965,0.0002235761,0.00005184296,0.0002337714,0.00009649426,0.00009775338],"domain_scores_gemma":[0.9992213,0.0002916569,0.0002283271,0.0001136221,0.00003962508,0.0001053802],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001625067,0.0001075644,0.9555553,0.00004376557,0.001975574,0.001197213,0.0001468695,0.0003625276,0.0334233,0.00007652837,0.0001988777,0.005287457],"study_design_scores_gemma":[0.00003713636,0.000179153,0.9975572,0.000002541726,0.000381759,0.0004975992,0.00004247354,0.0004579978,0.0005957654,0.00005362195,0.000189242,0.00000559413],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991128,0.0001611763,0.0003812916,0.00003273033,0.000006428037,0.000004774674,0.0001768202,0.00001349001,0.0001105413],"genre_scores_gemma":[0.9990004,0.00007765854,0.0003829471,0.0000248489,0.00001493208,0.00001093276,0.0003100902,0.000005087513,0.0001732203],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003207536,"threshold_uncertainty_score":0.006377757,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02720982952386061,"score_gpt":0.2258244677628558,"score_spread":0.1986146382389951,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}