{"id":"W2216745061","doi":"10.1038/ni.3308","title":"Type I interferon restricts type 2 immunopathology through the regulation of group 2 innate lymphoid cells","year":2015,"lang":"en","type":"article","venue":"Nature Immunology","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":331,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; McGill University Health Centre; Université de Montréal; Centre Hospitalier de l’Université de Montréal; McGill University","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Innate lymphoid cell; Immunology; Biology; Interferon; Cytokine; Immunopathology; STAT1; Innate immune system; IRF1; Interferon gamma; Transcription factor; Immune system; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002208446,0.0003337532,0.0001900634,0.0002248629,0.0002298126,0.0004447465,0.0001282068,0.0002313094,0.001861383],"category_scores_gemma":[0.000167446,0.0001112155,0.0001925606,0.0001130531,0.0002277745,0.0002724077,0.0003676793,0.0007129826,0.0004592076],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003038673,"about_ca_system_score_gemma":0.0003550656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002923796,"about_ca_topic_score_gemma":0.000735399,"domain_scores_codex":[0.9997477,0.00006093764,0.00001008486,0.00002661846,0.00006042099,0.00009415227],"domain_scores_gemma":[0.9998531,0.00002036997,0.00003790246,0.00001982763,0.00002359139,0.00004518809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001787425,0.00001952738,0.0006275227,0.00002380403,0.000002978245,0.00006700448,0.00002009559,0.0000790271,0.99467,0.0005394464,0.0002649889,0.003506918],"study_design_scores_gemma":[0.0001548236,0.000760661,0.07337145,0.0000828878,0.00004651096,0.001042976,0.000350687,0.004909975,0.89833,0.002646398,0.01827489,0.00002887727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9816383,0.003858548,0.005288021,0.0006507401,0.0001108134,0.00003950876,0.0002758989,0.0001372213,0.008000882],"genre_scores_gemma":[0.9941195,0.001083704,0.001038182,0.0001579669,0.00005300003,0.00003379793,0.0001723838,0.00002166568,0.00331981],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001861383,"threshold_uncertainty_score":0.006226957,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01625595015123413,"score_gpt":0.2458960880254855,"score_spread":0.2296401378742514,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}