{"id":"W2217332768","doi":"10.2203/dose-response.14-058.velegzhaninov","title":"Differential Molecular Stress Responses to Low Compared to High Doses of Ionizing Radiation in Normal Human Fibroblasts","year":2015,"lang":"en","type":"article","venue":"Dose-Response","topic":"Effects of Radiation Exposure","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Nuclear Laboratories","funders":"Russian Academy of Sciences","keywords":"Ionizing radiation; DNA damage; Low Dose Radiation; Gene; Comet assay; Biology; Gene expression; Radiobiology; Dose–response relationship; Irradiation; Dose dependence; DNA repair; Cell biology; Cancer research; Genetics; DNA; Medicine; Radiation therapy; Pharmacology; Internal medicine; Endocrinology; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008824754,0.0002496421,0.0004994379,0.0008898921,0.00005385793,0.00003806134,0.0002037356,0.0001333081,0.00007656783],"category_scores_gemma":[0.002668307,0.0002544853,0.00009213525,0.0006051361,0.00005205639,0.0001424381,0.00009734395,0.0001799835,0.00006641816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002689244,"about_ca_system_score_gemma":0.0002554334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001947279,"about_ca_topic_score_gemma":0.00005380131,"domain_scores_codex":[0.9970973,0.0009924801,0.0005393242,0.0003738834,0.0006246788,0.0003723267],"domain_scores_gemma":[0.9980072,0.0006277417,0.0001472737,0.0005077189,0.0002198909,0.0004901161],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.07637771,0.0003789038,0.0300748,0.00008248086,0.00004874964,0.0002020972,0.003258711,0.007131784,0.8807557,0.00007015797,0.001038259,0.0005805976],"study_design_scores_gemma":[0.004771916,0.00179755,0.6630339,0.0002824531,0.00003114234,0.00001240005,0.0002271525,0.0003475878,0.3290673,0.00001241669,0.0001994966,0.000216623],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964874,0.00005848266,0.0003844394,0.001722348,0.0002130948,0.0009502115,0.00007861364,0.00008122147,0.00002420912],"genre_scores_gemma":[0.9983816,6.182378e-7,0.000851644,0.0002441064,0.0001059852,0.00005818409,0.00006530969,0.0000451347,0.000247412],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6329591,"threshold_uncertainty_score":0.9999908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01772736946565551,"score_gpt":0.3062719995912431,"score_spread":0.2885446301255876,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}