{"id":"W2217650647","doi":"10.1159/000365810","title":"Rapid Aneuploidy Detection of Chromosomes 13, 18, 21, X and Y Using Quantitative Fluorescent Polymerase Chain Reaction with Few Microdissected Fetal Cells","year":2015,"lang":"en","type":"article","venue":"Fetal Diagnosis and Therapy","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal; Université de Sherbrooke","funders":"","keywords":"Molecular biology; Polymerase chain reaction; Aneuploidy; Biology; Microsatellite; Microdissection; Laser capture microdissection; Sexing; DNA; Multiple displacement amplification; genomic DNA; DNA extraction; Amniotic fluid; Real-time polymerase chain reaction; Fetus; Karyotype; Chromosome; Genetics; Allele; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001427499,0.0002076572,0.0003495522,0.0001224587,0.00008891267,0.00002787938,0.00003412754,0.0000958657,0.00001254593],"category_scores_gemma":[0.00007772828,0.0001564111,0.00005151667,0.0002068457,0.00016378,0.0001404411,0.00002230924,0.0001357719,0.00000162794],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003295586,"about_ca_system_score_gemma":0.00004720905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001240112,"about_ca_topic_score_gemma":0.00006372471,"domain_scores_codex":[0.998998,0.00007914877,0.0002176925,0.0002889678,0.0002173888,0.000198814],"domain_scores_gemma":[0.9991881,0.0001747728,0.0001452616,0.0001483695,0.0001175413,0.0002259097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003550983,0.0008853034,0.04271152,0.0001088691,0.0002624022,0.00008320488,0.0009117106,0.00001173029,0.8461043,0.00003009549,0.0001012938,0.1052385],"study_design_scores_gemma":[0.005184439,0.005004769,0.1149633,0.0004108179,0.0001477272,0.0001543399,0.0005827937,0.001421738,0.8714629,0.00003016291,0.0003602145,0.0002767747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854107,0.01356813,0.0002105838,0.0001303486,0.0001293679,0.0004156692,0.00004099675,0.00004439723,0.0000497338],"genre_scores_gemma":[0.9928038,0.006237417,0.0006866573,0.00008830846,0.00008562284,0.00002388877,0.00003410431,0.00002801768,0.0000121873],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1049618,"threshold_uncertainty_score":0.6378258,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04795841615785412,"score_gpt":0.2821647442558129,"score_spread":0.2342063280979588,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}