{"id":"W2218645201","doi":"10.1080/19491034.2015.1121355","title":"Totipotency in the absence of CAF-I: unhindered choices when the chaperone is out","year":2015,"lang":"en","type":"article","venue":"Nucleus","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Totipotent; Cell biology; Embryonic stem cell; Biology; Chromatin; Epigenome; Histone; Epigenetics; Telomere; Embryo; Genetics; DNA methylation; DNA; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000214434,0.0002065242,0.0003077971,0.0001545392,0.0003060058,0.0006603883,0.000312829,0.0004045698,0.0005936046],"category_scores_gemma":[0.0001636668,0.000126006,0.0001460668,0.00009168973,0.0008229174,0.0006459366,0.0003201465,0.000824787,0.000250444],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002919365,"about_ca_system_score_gemma":0.0002196598,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002908242,"about_ca_topic_score_gemma":0.0007836373,"domain_scores_codex":[0.9998974,0.00001576864,0.000005385962,0.00002528256,0.0000309524,0.00002526882],"domain_scores_gemma":[0.9999058,0.00002373191,0.00002158109,0.00001069873,0.00001552445,0.00002262947],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006473667,0.000006063156,0.0002623466,0.00004916919,0.000003433573,0.0003157721,0.0001276652,0.00005956211,0.9866008,0.006632203,0.0003277135,0.005550677],"study_design_scores_gemma":[0.00001631086,0.0002873801,0.005816579,0.00004454421,0.00004354559,0.001727174,0.0005026835,0.0008153105,0.8792797,0.008476065,0.1029493,0.00004142473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9338574,0.02237938,0.01693142,0.007081555,0.001380569,0.00002148031,0.0001413756,0.0003313439,0.0178754],"genre_scores_gemma":[0.9758331,0.01087952,0.002973637,0.001319632,0.0002868373,0.00001557372,0.00008620373,0.00009777938,0.00850771],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006603883,"threshold_uncertainty_score":0.00211823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02172708981085726,"score_gpt":0.2442825903604386,"score_spread":0.2225555005495814,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}