{"id":"W2219865542","doi":"10.1016/j.ijbiomac.2015.12.032","title":"Sulfated polysaccharide heparin used as carrier to load hydrophobic lappaconitine","year":2015,"lang":"en","type":"article","venue":"International Journal of Biological Macromolecules","topic":"Plant-based Medicinal Research","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"China Postdoctoral Science Foundation","keywords":"Heparin; Chemistry; Low molecular weight heparin; Dissolution; Polysaccharide; Analgesic; Polymer; Pharmacology; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002033116,0.0002233422,0.0003821359,0.0002875417,0.00005788588,0.00004846766,0.0009932854,0.0003176624,0.001110231],"category_scores_gemma":[0.003238176,0.0001623099,0.0001597731,0.0002252916,0.0002370331,0.00009196131,0.0002255496,0.001090545,0.000471156],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004113275,"about_ca_system_score_gemma":0.0007154417,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001614109,"about_ca_topic_score_gemma":0.00002240971,"domain_scores_codex":[0.9970292,0.0005316819,0.0006420981,0.0002532496,0.001080781,0.0004629508],"domain_scores_gemma":[0.9964852,0.0005995595,0.0002817341,0.000116788,0.001510172,0.001006504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005765675,0.000422952,0.009720427,0.00000485584,0.0005013167,0.006789128,0.0004755085,0.0002738518,0.9599882,0.0009417702,0.007030456,0.008085819],"study_design_scores_gemma":[0.008460303,0.004358724,0.004659809,0.0001475798,0.000125562,0.004831493,0.0008804199,0.000494677,0.7554651,0.004365334,0.2155913,0.0006196183],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872867,0.0004863833,0.0002065456,0.00670686,0.001668789,0.0001810526,0.0001350813,0.00003249452,0.003296049],"genre_scores_gemma":[0.9931918,0.0001625494,0.0002924256,0.005273225,0.0006519061,0.000008000998,0.00002094907,0.00001324596,0.0003859224],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2085609,"threshold_uncertainty_score":0.9998029,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2012053178559665,"score_gpt":0.4813764948262117,"score_spread":0.2801711769702452,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}