{"id":"W2220411799","doi":"10.1182/blood-2015-02-626390","title":"Hoxa cluster genes determine the proliferative activity of adult mouse hematopoietic stem and progenitor cells","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Université de Genève","keywords":"Haematopoiesis; Stem cell; Biology; Progenitor cell; Ectopic expression; Gene; Hematopoietic stem cell; Cell biology; Cancer research; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008387821,0.0002340506,0.0001118844,0.0004373799,0.0001227712,0.0002342312,0.0001015146,0.0001516835,0.0008187976],"category_scores_gemma":[0.00007560006,0.0001891849,0.0001035873,0.0001569562,0.0001783045,0.0001098142,0.0001697235,0.000297967,0.0004464588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002123757,"about_ca_system_score_gemma":0.0001234148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003974927,"about_ca_topic_score_gemma":0.0007329726,"domain_scores_codex":[0.9998847,0.00001018643,0.000008418487,0.00003324544,0.00003387826,0.00002955022],"domain_scores_gemma":[0.999895,0.00001539429,0.0000280606,0.00001014401,0.00001209947,0.00003929867],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003791526,0.000004225147,0.000424959,0.000006483006,0.000001455733,0.00001436892,0.000007846974,0.00001493833,0.9983763,0.00006362863,0.00001390531,0.001033988],"study_design_scores_gemma":[0.000006539743,0.00009476306,0.03225417,0.000003953344,0.00001375922,0.0001881931,0.00002790233,0.0003976023,0.9650917,0.00009720246,0.001821274,0.000002945692],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932672,0.001734594,0.002337322,0.00002797695,0.00000692583,0.00001192435,0.0007947913,0.00008984561,0.001729574],"genre_scores_gemma":[0.9922979,0.0009859536,0.00226068,0.00002588136,0.000007103122,0.00002438721,0.001015337,0.00003557825,0.003347063],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008187976,"threshold_uncertainty_score":0.002739131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01051492246582489,"score_gpt":0.2173873678018819,"score_spread":0.206872445336057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}