{"id":"W2220436775","doi":"10.2119/molmed.2010.00252","title":"Targeting IL-12/IL-23 by Employing a p40 Peptide-Based Vaccine Ameliorates TNBS-Induced Acute and Chronic Murine Colitis","year":2011,"lang":"en","type":"article","venue":"Molecular Medicine","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; Crohn's and Colitis Foundation of Canada; Crohn's and Colitis Foundation","keywords":"Interleukin 23; Molecular medicine; Colitis; Medicine; Immunology; Interleukin 17; Peptide; Inflammation; Cancer research; Biology; Internal medicine; Cancer; Cell cycle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001618457,0.0005944383,0.0005060382,0.0003274806,0.0001082109,0.0002575544,0.0001828189,0.0004221413,0.000601038],"category_scores_gemma":[0.0001024234,0.0001549677,0.0002796249,0.0001088249,0.0002993006,0.0002728207,0.0001406684,0.0009616013,0.0001364025],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001577526,"about_ca_system_score_gemma":0.000273275,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003498651,"about_ca_topic_score_gemma":0.0007199823,"domain_scores_codex":[0.9998152,0.00002341334,0.00002114529,0.00003048472,0.00004666203,0.0000630982],"domain_scores_gemma":[0.9998754,0.000009061554,0.00004508227,0.000008453316,0.0000122645,0.00004966935],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004368121,0.0003281739,0.0001498476,0.0000833045,0.000009431183,0.00005862959,0.00001322921,0.0001775123,0.9963715,0.00004014727,0.00004143445,0.002289963],"study_design_scores_gemma":[0.00025587,0.01156607,0.005883775,0.00004286109,0.0001090193,0.0005032858,0.00005299366,0.002496738,0.9760608,0.0001074728,0.002906963,0.00001419911],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956527,0.001428252,0.002031503,0.0001131327,0.0000682371,0.00005282885,0.00009731374,0.00009945175,0.0004564761],"genre_scores_gemma":[0.9941368,0.001443511,0.0024928,0.0001070623,0.0000404004,0.00005942015,0.0002384601,0.00002115763,0.001460333],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000601038,"threshold_uncertainty_score":0.002010643,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00935972759152993,"score_gpt":0.2337759974625304,"score_spread":0.2244162698710005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}