{"id":"W2220648092","doi":"10.1189/jlb.2hi0315-083r","title":"Endogenous and exogenous pathways maintain the reductive capacity of the phagosome","year":2015,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"Redox biology and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Phagolysosome; Phagosome; Biochemistry; Biology; Proteolysis; Thioredoxin; Thioredoxin reductase; Cell biology; Cysteine; Redox; Extracellular; Enzyme; Chemistry; Intracellular","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003099635,0.0002081227,0.0002300182,0.0001584042,0.0001577285,0.000516907,0.0002464576,0.0002917779,0.0005827795],"category_scores_gemma":[0.0002126952,0.00009801421,0.0001902854,0.0001087898,0.0002756153,0.0002962456,0.0002994636,0.000306213,0.0002547224],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002836309,"about_ca_system_score_gemma":0.0004173565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002890388,"about_ca_topic_score_gemma":0.0005159043,"domain_scores_codex":[0.9998096,0.00003564244,0.00001837293,0.00004610714,0.00004792661,0.00004239875],"domain_scores_gemma":[0.999851,0.00002221199,0.00003140349,0.00004479702,0.00002796597,0.00002257977],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007696596,0.00001316701,0.0002338172,0.00003099864,0.000004978159,0.00002988474,0.000009816566,0.00002817451,0.9980305,0.0002831394,0.00001330538,0.001245128],"study_design_scores_gemma":[0.000007745781,0.000116337,0.001520745,0.000005381416,0.0000141762,0.00010827,0.00003011927,0.0003331086,0.9955467,0.0001012579,0.002213482,0.000002746179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9816729,0.003960278,0.01189687,0.0001897591,0.00003739815,0.00005328016,0.0002750823,0.00009525393,0.001819165],"genre_scores_gemma":[0.9898101,0.001667387,0.006435809,0.00006895622,0.00001498725,0.00004248951,0.000328645,0.0000273056,0.001604278],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005827795,"threshold_uncertainty_score":0.00205785,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06002902258550712,"score_gpt":0.2583037099786384,"score_spread":0.1982746873931313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}