{"id":"W2220658591","doi":"10.15171/apb.2015.089","title":"Modulation of Cytokine Production and Transcription Factors Activities in Human Jurkat T Cells by Thymol and Carvacrol","year":2015,"lang":"en","type":"article","venue":"Advanced Pharmaceutical Bulletin","topic":"Essential Oils and Antimicrobial Activity","field":"Agricultural and Biological Sciences","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Shiraz University; Shiraz University of Medical Sciences","keywords":"Thymol; Carvacrol; Jurkat cells; NFAT; Chemistry; Molecular biology; Cytokine; Phorbol; Biochemistry; Pharmacology; T cell; Biology; Immunology; Transcription factor; Protein kinase C; Food science; Phosphorylation; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001312604,0.0001125821,0.0001664842,0.0000114791,0.00006340774,0.00001802934,0.00003957344,0.00005781363,0.00003830492],"category_scores_gemma":[0.00002054764,0.0000558077,0.0000238016,0.00009192553,0.0001042331,0.0001435424,0.00002274674,0.0001169318,7.393703e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001570484,"about_ca_system_score_gemma":0.000002048304,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001746573,"about_ca_topic_score_gemma":0.00007635356,"domain_scores_codex":[0.9992704,0.00007035946,0.000158361,0.0002373778,0.0001098269,0.0001536612],"domain_scores_gemma":[0.9997575,0.00005067965,0.00005507191,0.00002294589,0.00002759462,0.00008624726],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007934897,0.0001113514,0.001983993,0.00002005414,0.000003378182,4.721028e-7,0.0001225762,0.00004055137,0.9848613,0.00002584861,0.00009998894,0.01265115],"study_design_scores_gemma":[0.0003213788,0.0001290095,0.007533111,0.00002668193,0.00001042473,0.0000016761,0.0001996065,0.00007488745,0.9833248,0.0001136378,0.008135432,0.0001293938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982715,0.0001426458,0.00001136528,0.001192055,0.0000786543,0.0001908984,0.00003793385,0.00002027377,0.00005472282],"genre_scores_gemma":[0.9996107,0.0001535337,0.00005146716,0.00004311135,0.00004146682,0.000004848008,0.00002500008,0.000001356069,0.0000685751],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01252175,"threshold_uncertainty_score":0.2275772,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02853943379363423,"score_gpt":0.2678886164991866,"score_spread":0.2393491827055524,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}