{"id":"W2221173327","doi":"10.1186/s12896-015-0228-7","title":"Development and characterization of a eukaryotic expression system for human type II procollagen","year":2015,"lang":"en","type":"article","venue":"BMC Biotechnology","topic":"Collagen: Extraction and Characterization","field":"Materials Science","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Innovative Medicines Canada; University of British Columbia; Memorial University of Newfoundland; Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Michael Smith Health Research BC; Canada Foundation for Innovation","keywords":"Procollagen peptidase; Biology; Circular dichroism; Biophysics; Biochemistry; Fibril; Recombinant DNA; Cell biology; Molecular biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007261536,0.0005523844,0.0002831031,0.0003960438,0.0002913698,0.0004730582,0.0003867567,0.0004453035,0.001236345],"category_scores_gemma":[0.0004501649,0.0002283799,0.0004321544,0.0003894694,0.0002312777,0.0002756744,0.0002846976,0.0007818905,0.001434181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005530313,"about_ca_system_score_gemma":0.0005257274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007110212,"about_ca_topic_score_gemma":0.0009607913,"domain_scores_codex":[0.999549,0.00006485444,0.00007529743,0.00009510603,0.0001702316,0.00004542695],"domain_scores_gemma":[0.9997,0.00006719922,0.00005685263,0.00005221899,0.00008807247,0.00003570704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002265913,0.00002368823,0.0001246196,0.00004721798,0.000004185937,0.00003913725,0.00001969326,0.00008576515,0.9977496,0.000145166,0.0001123985,0.001625834],"study_design_scores_gemma":[0.00002091966,0.00019828,0.001834217,0.00001886933,0.00002642037,0.0003456761,0.00001940602,0.00139998,0.9816922,0.00007583699,0.01435524,0.00001286669],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6673514,0.005270395,0.302608,0.001089047,0.0003548097,0.001535669,0.01302221,0.0009980618,0.007770391],"genre_scores_gemma":[0.6086462,0.004282058,0.3355549,0.0003764271,0.00009357138,0.0009220432,0.04072395,0.0003599958,0.009040981],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001236345,"threshold_uncertainty_score":0.004136026,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04391698957556447,"score_gpt":0.2664646013292177,"score_spread":0.2225476117536533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}