{"id":"W2221715624","doi":"10.1016/j.jsbmb.2015.12.002","title":"Calcitriol and 20(S)-protopanaxadiol synergistically inhibit growth and induce apoptosis in human prostate cancer cells","year":2015,"lang":"en","type":"article","venue":"The Journal of Steroid Biochemistry and Molecular Biology","topic":"Ginseng Biological Effects and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"Vancouver General Hospital; University of British Columbia","funders":"Ministry of Higher Education and Scientific Research; Ministry of Education, Libya","keywords":"LNCaP; Calcitriol; Calcitriol receptor; Prostate cancer; Androgen receptor; Cancer research; Cell growth; Protopanaxadiol; Viability assay; Cell cycle; Apoptosis; Chemistry; Biology; Cancer; Pharmacology; Internal medicine; Endocrinology; Vitamin D and neurology; Medicine; Ginsenoside; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000299344,0.0006197778,0.0007141124,0.001068343,0.000596712,0.0004078339,0.0004302424,0.0004210847,0.003330029],"category_scores_gemma":[0.0002553154,0.0003239139,0.0006861218,0.001031015,0.0004453209,0.0003038513,0.0003873382,0.0008547637,0.0006793995],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006682369,"about_ca_system_score_gemma":0.00125499,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00553795,"about_ca_topic_score_gemma":0.009663036,"domain_scores_codex":[0.9996024,0.00007095031,0.00003573796,0.00004930851,0.000099679,0.0001418807],"domain_scores_gemma":[0.9998059,0.00005821135,0.00001930162,0.00003080439,0.00002727913,0.0000585128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003675527,0.0006797648,0.0008276671,0.0002302672,0.0000502703,0.0004194949,0.0001833278,0.0002706409,0.9854753,0.0002309474,0.0006418544,0.007315043],"study_design_scores_gemma":[0.0002892604,0.002918316,0.006412307,0.00000947696,0.00008353133,0.0005400427,0.0001846492,0.0005226503,0.9834086,0.00009393364,0.005523128,0.00001406122],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865726,0.006486287,0.0007524909,0.0003493192,0.0002025402,0.00009564377,0.0006013412,0.0002068569,0.004732866],"genre_scores_gemma":[0.9898676,0.002877839,0.0009147132,0.000124312,0.00005415921,0.00009108464,0.0008888748,0.00002375954,0.005157682],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00553795,"threshold_uncertainty_score":0.01114005,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01088776899115353,"score_gpt":0.2752037149960362,"score_spread":0.2643159460048827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}