{"id":"W2222591283","doi":"10.1038/onc.2015.485","title":"Suppressor of cytokine signaling 1-dependent regulation of the expression and oncogenic functions of p21CIP1/WAF1 in the liver","year":2016,"lang":"en","type":"article","venue":"Oncogene","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Université de Sherbrooke","funders":"Fonds de recherche du Québec – Nature et technologies; Fonds de Recherche du Québec - Santé; Canadian Liver Foundation","keywords":"Suppressor of cytokine signaling 1; SOCS2; Biology; SOCS3; Cytokine; Suppressor of cytokine signalling; Cancer research; Tumor suppressor gene; Gene knockdown; SOCS6; Suppressor; Carcinogenesis; Downregulation and upregulation; Signal transduction; Cell biology; Apoptosis; Immunology; STAT3; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001870447,0.0004130979,0.0002514194,0.0006640415,0.0003401844,0.0004949247,0.0001836331,0.0002013089,0.002433988],"category_scores_gemma":[0.000301201,0.0002174233,0.0002917309,0.0002567701,0.0003329383,0.0003907422,0.0002929368,0.0006999953,0.0007167452],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004498816,"about_ca_system_score_gemma":0.0003873175,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000804404,"about_ca_topic_score_gemma":0.0009426501,"domain_scores_codex":[0.9998146,0.00002963139,0.000012711,0.00001817893,0.00004243335,0.00008249951],"domain_scores_gemma":[0.9998105,0.00002751989,0.00004890461,0.00002373879,0.00003538912,0.00005393788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007945054,0.00007277831,0.0009663695,0.00005734722,0.000007879518,0.0002778461,0.00005189306,0.0001472496,0.9928947,0.0007528092,0.0003472935,0.003629352],"study_design_scores_gemma":[0.00008895664,0.0003716892,0.05090888,0.00001426817,0.00003432421,0.001207119,0.0001548344,0.002448091,0.9366763,0.0005338942,0.007549761,0.00001180078],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919717,0.003029024,0.001127402,0.0003331808,0.00004889428,0.00002070176,0.0004379356,0.00008739936,0.002943788],"genre_scores_gemma":[0.9949404,0.00103456,0.0004128556,0.00004639946,0.00002486976,0.00002722891,0.0004854895,0.00001486077,0.003013316],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002433988,"threshold_uncertainty_score":0.008142471,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02579936461080412,"score_gpt":0.2624293414085712,"score_spread":0.236629976797767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}