{"id":"W2223073505","doi":"10.1200/jco.2012.30.15_suppl.tps1136","title":"ANZ1001 SORBET: Study of estrogen receptor beta and efficacy of tamoxifen, a single arm, phase II study of the efficacy of tamoxifen in triple-negative but estrogen receptor beta-positive metastatic breast cancer.","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"","keywords":"Medicine; Tamoxifen; Triple-negative breast cancer; Breast cancer; Estrogen receptor; Internal medicine; Oncology; Metastatic breast cancer; Progesterone receptor; Clinical endpoint; Estrogen; Cancer; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004022599,0.002404156,0.002593437,0.000972841,0.000477384,0.0009509474,0.001659862,0.002123781,0.008978655],"category_scores_gemma":[0.00192347,0.001063305,0.001619235,0.0005545404,0.00127682,0.0008814991,0.0005726314,0.003183706,0.00235983],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008087241,"about_ca_system_score_gemma":0.002542905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001032522,"about_ca_topic_score_gemma":0.002916575,"domain_scores_codex":[0.9984661,0.001072726,0.00003224802,0.0001169,0.0001770555,0.0001349182],"domain_scores_gemma":[0.9986207,0.0002856024,0.0002263208,0.00008212579,0.0001015398,0.0006836482],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8581758,0.03581897,0.003450176,0.001521289,0.00126505,0.0002705232,0.0001917013,0.001978449,0.02331433,0.0005277593,0.006843787,0.06664214],"study_design_scores_gemma":[0.7953209,0.1953275,0.004374686,0.0000349065,0.0002366574,0.0001452002,0.00001891156,0.0005088152,0.0008105663,0.0001360851,0.003065249,0.00002061157],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9665877,0.004847249,0.001311692,0.001923851,0.0004006092,0.01232954,0.00474996,0.0003368244,0.007512447],"genre_scores_gemma":[0.9268961,0.006047462,0.00648775,0.003835329,0.0006690244,0.02193389,0.009026758,0.0001790599,0.02492465],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008978655,"threshold_uncertainty_score":0.03003663,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05189851969657101,"score_gpt":0.4041094689279967,"score_spread":0.3522109492314257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}