{"id":"W2223761815","doi":"10.1016/s0923-7534(20)31970-0","title":"Randomized Phase 3 Trial of Regorafenib in Patients (Patients) with Metastatic and/or Unresectable Gastrointestinal Stromal Tumor (GIST) Progressing Despite Prior Treatment with at Least Imatinib (IM) and Sunitinib (SU) : Grid Trial","year":2012,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Gastrointestinal Tumor Research and Treatment","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital","funders":"","keywords":"Regorafenib; Medicine; GiST; Sunitinib; Imatinib; Oncology; Internal medicine; Sunitinib malate; Stromal tumor; Stromal cell; Colorectal cancer; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001236069,0.001632902,0.002401132,0.0002951386,0.0003490098,0.0009672555,0.0008914151,0.00117714,0.008886428],"category_scores_gemma":[0.001394094,0.0005202382,0.001851951,0.0003457145,0.001323314,0.001092024,0.00057778,0.003038144,0.001704241],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001084024,"about_ca_system_score_gemma":0.001459566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001958382,"about_ca_topic_score_gemma":0.005805371,"domain_scores_codex":[0.9996091,0.0002023288,0.00001504361,0.00007892684,0.00001996611,0.00007468739],"domain_scores_gemma":[0.9993236,0.0001367192,0.0001563055,0.00008293378,0.00002879839,0.0002716528],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9651921,0.003104049,0.001437962,0.0004314823,0.0009405651,0.00008347163,0.00006417398,0.001363857,0.002471082,0.0003290053,0.005312321,0.01926993],"study_design_scores_gemma":[0.9776064,0.01882895,0.001349019,0.000014332,0.0001747315,0.00006392426,0.00002155109,0.0003164787,0.0001689407,0.0003138644,0.001130564,0.00001121717],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9765453,0.004342057,0.001129792,0.002732859,0.00087674,0.003206538,0.005244796,0.0004592008,0.005462842],"genre_scores_gemma":[0.9761593,0.002313022,0.002810194,0.003257086,0.0003484812,0.004130057,0.005122638,0.00008355649,0.005775637],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008886428,"threshold_uncertainty_score":0.02972806,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09573382842189562,"score_gpt":0.3966884140924295,"score_spread":0.3009545856705339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}