{"id":"W2224857357","doi":"10.1161/circ.130.suppl_2.15610","title":"Abstract 15610: The Infusion of Mesenchymal Stromal Cells Post Myocardial Infarction Increases Myocardial S100A6, Attenuates Myocyte Hypertrophy, Reduces Myocyte Apoptosis and Improves Cardiac Function","year":2014,"lang":"en","type":"article","venue":"Circulation","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; St. Michael's Hospital","funders":"","keywords":"Medicine; Myocyte; Mesenchymal stem cell; Apoptosis; Calphostin C; Cardiac function curve; Paracrine signalling; Cardiac myocyte; Internal medicine; Endocrinology; Andrology; Heart failure; Pathology; Protein kinase C; Kinase; Cell biology; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001562076,0.000848103,0.000677414,0.0003032529,0.0001757697,0.0002905786,0.0002626314,0.0005821147,0.007277125],"category_scores_gemma":[0.00009886175,0.0002119436,0.0003851755,0.0001839616,0.0004179127,0.0002573875,0.0002224353,0.001416796,0.001930655],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003344498,"about_ca_system_score_gemma":0.0004721583,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004487716,"about_ca_topic_score_gemma":0.0007583285,"domain_scores_codex":[0.9998361,0.00001812334,0.00002169836,0.00003434839,0.00004864992,0.00004114172],"domain_scores_gemma":[0.9998521,0.00001248486,0.00004023936,0.00001104904,0.00001249313,0.0000715604],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001028082,0.0002559395,0.0001015599,0.000104391,0.000008222594,0.00006087722,0.00001126391,0.00002298355,0.9956049,0.00005500795,0.0002642707,0.002482708],"study_design_scores_gemma":[0.0003208919,0.003683072,0.004134385,0.00002253507,0.00003780199,0.0002996389,0.00002905262,0.0002876467,0.9861971,0.00004375813,0.004937985,0.000006095227],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876118,0.00341639,0.001884804,0.0006997598,0.0004547816,0.0001309041,0.001554664,0.0003592274,0.003887613],"genre_scores_gemma":[0.9588677,0.003397485,0.004339349,0.0004973109,0.0002244923,0.0003624522,0.003566546,0.0001109941,0.02863376],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007277125,"threshold_uncertainty_score":0.02434444,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00580245962089697,"score_gpt":0.201986454846531,"score_spread":0.196183995225634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}