{"id":"W2227971208","doi":"10.14785/lpsn-2015-0013","title":"Autosomal dominant transmission of signal transduction and activator of transcription 1 (STAT1) mutation (Thr385Met) and extended lifespan","year":2016,"lang":"en","type":"article","venue":"LymphoSign Journal","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Primary immunodeficiency; Biology; Immunodeficiency; STAT1; Mutation; Sepsis; Immunology; Genetics; Medicine; Signal transduction; Gene; Immune system","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003934985,0.0001599848,0.0003074037,0.0001756566,0.0001948789,0.000009375403,0.00008781888,0.0001743605,0.0003163677],"category_scores_gemma":[0.00001729244,0.0001075133,0.000104645,0.00009678976,0.0003678433,0.0003194216,0.000006257723,0.0001249909,0.000002027351],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003244809,"about_ca_system_score_gemma":0.0001295691,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002634724,"about_ca_topic_score_gemma":3.267712e-7,"domain_scores_codex":[0.998804,0.0001983539,0.0005158155,0.000182888,0.00007099588,0.0002279045],"domain_scores_gemma":[0.9994447,0.00009119415,0.0002836311,0.0000839446,0.00007826349,0.00001826983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008726116,0.0001345043,0.00006957178,0.00003373128,0.00006385246,0.000001730325,0.002532303,0.000002155998,0.7231809,0.0002423753,0.000007375343,0.2728589],"study_design_scores_gemma":[0.005825004,0.0008503868,0.01243816,0.0002940416,0.00009999623,0.0008638009,0.001005942,0.00002533312,0.9759185,0.001201499,0.001315812,0.0001614893],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9189882,0.01565982,0.06459597,0.0003086441,0.0002440309,0.0001389274,0.00001285361,0.00001253951,0.00003905228],"genre_scores_gemma":[0.9983242,0.001371837,0.0001629067,0.00001220497,0.000005929684,0.000003729475,0.000005038296,0.00001244443,0.0001017749],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2726974,"threshold_uncertainty_score":0.4384266,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007079102152865378,"score_gpt":0.2137727482885367,"score_spread":0.2066936461356713,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}