{"id":"W2228463059","doi":"10.1039/c5cc09163b","title":"One-pot peptide and protein conjugation: a combination of enzymatic transamidation and click chemistry","year":2016,"lang":"en","type":"article","venue":"Chemical Communications","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Click chemistry; Chemistry; Peptide; Enzyme; Protein chemistry; Combinatorial chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001196912,0.000142182,0.0002055286,0.00001772744,0.0001390681,0.00002296879,0.0003911346,0.0001571903,0.0001761764],"category_scores_gemma":[0.0002221637,0.0001368783,0.00004499585,0.0001228675,0.0005954647,0.0001325779,0.0001668674,0.0001704672,0.000005175118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004903644,"about_ca_system_score_gemma":0.00003412399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008527836,"about_ca_topic_score_gemma":0.000002066134,"domain_scores_codex":[0.999008,0.00001901925,0.0004364937,0.0002513918,0.0001446701,0.000140447],"domain_scores_gemma":[0.99812,0.0004159278,0.0002127862,0.001006992,0.0001346753,0.0001096102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001178996,0.0002005899,0.0001997747,0.0002833279,0.00002254484,4.147424e-8,0.0001409094,4.780387e-8,0.9898958,0.004449332,0.00005317046,0.004742635],"study_design_scores_gemma":[0.0008417849,0.000005796278,0.0001911821,0.0002991999,0.00004426763,0.000006476468,0.0001035465,0.000158044,0.9883864,0.006606863,0.003185547,0.0001709204],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9789333,0.0002655755,0.0005140192,0.005879698,0.000002341322,0.0001751111,0.00007294681,0.00008266304,0.0140743],"genre_scores_gemma":[0.9963191,0.0002317602,0.002006074,0.00002893006,0.00002399839,0.0002425374,0.0001662443,0.00001692179,0.0009644855],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01738571,"threshold_uncertainty_score":0.5581737,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02893178727457233,"score_gpt":0.2588729439218267,"score_spread":0.2299411566472544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}