{"id":"W2228463059","doi":"10.1039/c5cc09163b","title":"One-pot peptide and protein conjugation: a combination of enzymatic transamidation and click chemistry","year":2016,"lang":"en","type":"article","venue":"Chemical Communications","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Click chemistry; Chemistry; Peptide; Enzyme; Protein chemistry; Combinatorial chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006346914,0.001106493,0.0006426041,0.0003749725,0.0002234946,0.0004794288,0.0006135719,0.0006774034,0.001095086],"category_scores_gemma":[0.0004192071,0.0003853163,0.0004231586,0.0004245755,0.000399811,0.0006024095,0.0006784335,0.001004304,0.0009353363],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002781259,"about_ca_system_score_gemma":0.0003798481,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001781651,"about_ca_topic_score_gemma":0.0003844986,"domain_scores_codex":[0.9994999,0.00005480181,0.00004988439,0.0001480259,0.0001525813,0.00009466304],"domain_scores_gemma":[0.9997811,0.00004519863,0.00005490094,0.00004498396,0.00003106171,0.00004274919],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006511511,0.00007341869,0.00009407882,0.00008259244,0.00001496905,0.0001917287,0.0000278702,0.000139424,0.9935625,0.0004097919,0.0001081432,0.005230365],"study_design_scores_gemma":[0.00001264233,0.0002666673,0.0003158986,0.000002638387,0.0000118584,0.0006776213,0.000005397179,0.0004695333,0.9964167,0.00007588829,0.001734387,0.00001078448],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7704673,0.002047542,0.2180827,0.000324488,0.0002268281,0.0008027281,0.0005269085,0.001648348,0.005873194],"genre_scores_gemma":[0.9330819,0.001463598,0.05759446,0.0001519144,0.00003560757,0.0003486265,0.0006051002,0.0001627046,0.006556028],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001106493,"threshold_uncertainty_score":0.003663421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02893178727457233,"score_gpt":0.2588729439218267,"score_spread":0.2299411566472544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}