{"id":"W2228937735","doi":"10.1021/jacs.5b08523","title":"Direct DNA Analysis with Paper-Based Ion Concentration Polarization","year":2015,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Biosensors and Analytical Detection","field":"Engineering","cited_by":139,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Royal Victoria Hospital; University of Toronto; University of New Brunswick","funders":"Canadian Institutes of Health Research; Canada Foundation for Innovation; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Chemistry; DNA fragmentation; DNA; Detection limit; Sperm; Chromatin; Nanotechnology; Molecular biology; Chromatography; Computational biology; Biophysics; Apoptosis; Biochemistry; Genetics; Materials science; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00068423,0.0009744058,0.0003570423,0.0006461848,0.0002647503,0.0008171417,0.0008432672,0.001119571,0.002182803],"category_scores_gemma":[0.001771717,0.0003880154,0.0003717104,0.0005931315,0.0007318596,0.0008212356,0.0009753281,0.001027228,0.001425104],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002824733,"about_ca_system_score_gemma":0.0002126599,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001695117,"about_ca_topic_score_gemma":0.0002498373,"domain_scores_codex":[0.9988095,0.0002344116,0.00005530708,0.0003143449,0.0005277104,0.00005877389],"domain_scores_gemma":[0.9982603,0.0009266203,0.0003020715,0.0001778122,0.0002825226,0.00005070567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004429244,0.00001784869,0.0005793949,0.00009105464,0.00001610398,0.00004794359,0.00003107942,0.00007737242,0.9903365,0.0001160515,0.0001508702,0.008491542],"study_design_scores_gemma":[0.000005578655,0.0001019147,0.0009814544,0.00001171072,0.0000119504,0.000288067,0.00003118226,0.0009024202,0.9954553,0.0001497968,0.002049749,0.00001097436],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.4874009,0.008245838,0.4876765,0.000941131,0.0005808063,0.0003677233,0.001312195,0.002330522,0.01114433],"genre_scores_gemma":[0.6138732,0.00879338,0.361298,0.001178593,0.0002929605,0.0006049656,0.001023701,0.0002413164,0.01269388],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.002182803,"threshold_uncertainty_score":0.007302225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006892446718450666,"score_gpt":0.2041258641969079,"score_spread":0.1972334174784572,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}